Evidence map›Paper›PMID 35950117›Full record

ReviewPostepy dermatologii i alergologii2022

Resveratrol as a factor preventing skin aging and affecting its regeneration.

Kamil Leis, Karolina Pisanko, Arkadiusz Jundziłł, Ewelina Mazur, Kaja Mêcińska-Jundziłł, Henryk Witmanowski

Open access · goldAbstract readReview
In one paragraph

Review in Postepy dermatologii i alergologii, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Food as Medicine for Hypertension: Microbiota as Mediators.Hypertension (Dallas, Tex. : 1979) · 2025
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  17. Research Progress on Skin Aging and Active Ingredients.Molecules (Basel, Switzerland) · 2023
    Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Kamil LeisDepartment of Plastic, Reconstructive and Aesthetic Surgery, Faculty of Medicine in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.
Karolina PisankoDepartment of Plastic, Reconstructive and Aesthetic Surgery, Faculty of Medicine in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.
Arkadiusz JundziłłDepartment of Plastic, Reconstructive and Aesthetic Surgery, Faculty of Medicine in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.
Ewelina MazurDepartment of Plastic, Reconstructive and Aesthetic Surgery, Faculty of Medicine in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.
Kaja Mêcińska-JundziłłDepartment of Dermatology and Venerology, Faculty of Medicine in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.
Henryk WitmanowskiDepartment of Plastic, Reconstructive and Aesthetic Surgery, Faculty of Medicine in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.
Nicolaus Copernicus University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Resveratrol, a compound belonging to polyphenols, besides its action on the cardiovascular system, affects also wound healing, regeneration, and photoaging of the skin. By interactions with numerous substances and pathways, e.g. MAPK, MAPKK, FOXO3, TGF or metalloproteinase 1, it protects the skin against the harmful effects of type B ultraviolet radiation, which is the main factor in the skin aging processes. It also enhances collagen synthesis by activating the oestrogen receptor and reduces wrinkles. In damaged tissues, it accelerates skin regeneration and healing by activating, among others, VEGF. Based on the review of the literature, there is no doubt that resveratrol has the potential to be used in cosmetology, dermatology and plastic surgery. It can be used as a compound of anti-aging products or as a topical treatment of scars and wounds. In the future this polyphenol might be applied in pharmacotherapy of many dermatoses.

Indexed as

polyphenolsresveratrolskin agingskin regeneration

Identifiers

PMID35950117
PMCPMC9326919
OpenAlexW4285614196

What Socratic holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.