Evidence mapPaperPMID 35954327Full record

ReviewCancers2022

Li-Fraumeni Syndrome: Mutation of

Valentina Rocca, Giovanni Blandino, Lucia D'Antona, Rodolfo Iuliano, Silvia Di Agostino

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 38 citations in OpenAlex.

  1. ComplexInternational journal of molecular sciences · 2026
    Review
  2. TruncatingJournal of cancer prevention · 2026
    Article
  3. Double jeopardy: howFrontiers in cell and developmental biology · 2026
    Review
  4. Article
  5. TP53 mutations and MDM2 polymorphisms in breast and ovarian cancers: amelioration by drugs and natural compounds.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Whole-Exome Analysis and Osteosarcoma: A Game Still Open.International journal of molecular sciences · 2024
    Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Case report: A germlineFrontiers in oncology · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Valentina RoccaDepartment of Clinical and Experimental Medicine, Magna Græcia University of Catanzaro, 88100 Catanzaro, Italy.
Giovanni BlandinoTranslational Oncology Research Unit, IRCCS Regina Elena National Cancer Institute, Via Elio Chianesi, 53, 00144 Rome, Italy.
Lucia D'AntonaMedical Genetics Unit, Mater Domini University Hospital, 88100 Catanzaro, Italy.
Rodolfo IulianoMedical Genetics Unit, Mater Domini University Hospital, 88100 Catanzaro, Italy.ORCID 0000-0002-8524-7402
Silvia Di AgostinoDepartment of Health Sciences, Magna Græcia University of Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0003-3730-1125
Magna Graecia University · ITIstituti di Ricovero e Cura a Carattere Scientifico · IT

Funding

Italian Association for Cancer Research 22759
6 · The paper itself

Abstract

Li-Fraumeni syndrome (LFS) is a rare familial tumor predisposition syndrome with autosomal dominant inheritance, involving germline mutations of the

Indexed as

biomarkercancer predispositiongermline mutationLi–Fraumeni syndrome (LFS)TP53

Identifiers

PMID35954327
PMCPMC9367397
OpenAlexW4288060409

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.