Evidence map›Paper›PMID 35955474›Full record

ArticleInternational journal of molecular sciences2022

Simvastatin Inhibits

Trang Thi Nguyen, Heejin Kim, Tran Xuan Ngoc Huy, Wongi Min, Hujang Lee, Alisha Wehdnesday Bernardo Reyes, Johnhwa Lee, Suk Kim

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Trang Thi NguyenInstitute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Korea.ORCID 0000-0003-1903-7885
Heejin KimInstitute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Korea.
Tran Xuan Ngoc HuyInstitute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Korea.ORCID 0000-0001-7065-7276
Wongi MinInstitute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Korea.ORCID 0000-0003-2437-7366
Hujang LeeInstitute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Korea.ORCID 0000-0002-7552-6416
Alisha Wehdnesday Bernardo ReyesDepartment of Veterinary Paraclinical Sciences, College of Veterinary Medicine, University of the Philippines Los Baños, Los Baños 4031, Philippines.
Johnhwa LeeCollege of Veterinary Medicine, Chonbuk National University, Iksan 54596, Korea.
Suk KimInstitute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Korea.ORCID 0000-0001-5795-2019
Gyeongsang National University · KRJeonbuk National University · KRUniversity of the Philippines Los Baños · PH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Simvastatin is an inhibitor of 3-hydroxy-3-methylglutaryl CoA reductase and has been found to have protective effects against several bacterial infections. In this study, we investigate the effects of simvastatin treatment on RAW 264.7 macrophage cells and ICR mice against

Indexed as

Brucella abortusBrucellosisAnimalsCD8-Positive T-LymphocytesDisease Models, AnimalMevalonic AcidMiceMice, Inbred ICRRAW 264.7 CellsSimvastatinMevalonic AcidSimvastatinBrucella abortusICR mouseimmune responsemevalonate pathwayphagocytosisRAW 264.7 cellsimvastatin

Identifiers

PMID35955474
PMCPMC9368445
OpenAlexW4288441614

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.