Evidence map›Paper›PMID 35955745›Full record

ReviewInternational journal of molecular sciences2022

Aquatic Freshwater Vertebrate Models of Epilepsy Pathology: Past Discoveries and Future Directions for Therapeutic Discovery.

Rachel E Williams, Karen Mruk

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Effect of Voltage-Gated KbioRxiv : the preprint server for biology · 2024
    Article
  2. Molecular Insights into IQSEC2 Disease.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Rachel E WilliamsSchool of Pharmacy, College of Health Sciences, University of Wyoming, Laramie, WY 82071, USA.
Karen MrukSchool of Pharmacy, College of Health Sciences, University of Wyoming, Laramie, WY 82071, USA.ORCID 0000-0003-4560-4951

Funding

Zebrafish Models of CNS Injury and Locomotor RecoveryP20GM121310 · NIGMS · UNIVERSITY OF WYOMING · PI ZHAOJIE ZHANG · 2017 to 2026
$27.2M
RNA-based tools for developmental and regenerative biologyR21GM143565 · NIGMS · UNIVERSITY OF WYOMING · PI MCKEAGUE, MAUREEN HOPE, MRUK, KAREN · 2021 to 2022
$356k
NIGMS NIH HHS P20 GM121310NIGMS NIH HHS R21 GM143565NIH HHS GM143565 and GM121310
6 · The paper itself

Abstract

Epilepsy is an international public health concern that greatly affects patients' health and lifestyle. About 30% of patients do not respond to available therapies, making new research models important for further drug discovery. Aquatic vertebrates present a promising avenue for improved seizure drug screening and discovery. Zebrafish (

Indexed as

EpilepsyZebrafishAnimalsDrug Evaluation, PreclinicalFresh WaterHumansSeizuresXenopus laevisdrug developmentdrug screeningseizuresXenopus laeviszebrafish

Identifiers

PMID35955745
PMCPMC9368815

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.