Evidence map›Paper›PMID 35955842›Full record

ArticleInternational journal of molecular sciences2022

Microbial Type IA Topoisomerase C-Terminal Domain Sequence Motifs, Distribution and Combination.

Brenda Diaz, Christopher Mederos, Kemin Tan, Yuk-Ching Tse-Dinh

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
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  7. Review
  8. Localization ofFrontiers in microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Brenda DiazDepartment of Chemistry and Biochemistry, Florida International University, Miami, FL 33199, USA.
Christopher MederosDepartment of Chemistry and Biochemistry, Florida International University, Miami, FL 33199, USA.
Kemin TanStructural Biology Center, X-ray Science Division, Advanced Photon Source, Argonne National Laboratory, 9700 S. Cass Avenue, Lemont, IL 60439, USA.ORCID 0000-0002-4003-7903
Yuk-Ching Tse-DinhDepartment of Chemistry and Biochemistry, Florida International University, Miami, FL 33199, USA.ORCID 0000-0002-5616-5176
Florida International University · USArgonne National Laboratory · US

Funding

Supplement for undergraduate research participant to promote diversityR01GM054226 · NIGMS · NEW YORK MEDICAL COLLEGE · PI TSE-DINH, YUK-CHING · 1996 to 2020
$4.6M
Structure, Mechanism and Interactions of Type IA TopoisomerasesR35GM139817 · NIGMS · FLORIDA INTERNATIONAL UNIVERSITY · PI TSE-DINH, YUK-CHING · 2021 to 2025
$1.6M
NIGMS NIH HHS R01 GM054226NIGMS NIH HHS R35 GM139817NIH HHS R35GM139817
6 · The paper itself

Abstract

Type IA topoisomerases have highly conserved catalytic N-terminal domains for the cleaving and rejoining of a single DNA/RNA strand that have been extensively characterized. In contrast, the C-terminal region has been less covered. Two major types of small tandem C-terminal domains, Topo_C_ZnRpt (containing C4 zinc finger) and Topo_C_Rpt (without cysteines) were initially identified in

Indexed as

DNADNA Topoisomerases, Type IEscherichia coliProtein DomainsZinc FingersDNADNA Topoisomerases, Type ITop3TopAtopoisomerasetype IAzf-CCHCzf-GRFzinc fingers

Identifiers

PMID35955842
PMCPMC9369019
OpenAlexW4290592282

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.