Evidence map›Paper›PMID 35957539›Full record

ArticleCell cycle (Georgetown, Tex.)2022

Upregulated miR-322-5p regulates cell cycle and promotes cell proliferation and apoptosis by directly targeting Wee1 in mice liver injury.

He Tong, Li Wang, Jing Shi, Haowei Jin, Kefan Zhang, Yulong Bao, Yongshuai Wu, Yipeng Cheng, Pengxia Liu, Changshan Wang

Open access · greenAbstract read
In one paragraph

Article in Cell cycle (Georgetown, Tex.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

He TongSchool of Life Science, Inner Mongolia University, Hohhot, Inner, China.ORCID 0000-0003-3149-7243
Li WangSchool of Life Science, Inner Mongolia University, Hohhot, Inner, China.
Jing ShiSchool of Life Science, Inner Mongolia University, Hohhot, Inner, China.
Haowei JinSchool of Life Science, Inner Mongolia University, Hohhot, Inner, China.
Kefan ZhangSchool of Life Science, Inner Mongolia University, Hohhot, Inner, China.
Yulong BaoSchool of Basic Medicine, Inner Mongolia Medical University, Hohhot, Inner, China.
Yongshuai WuSchool of Life Science, Inner Mongolia University, Hohhot, Inner, China.
Yipeng ChengSchool of Life Science, Inner Mongolia University, Hohhot, Inner, China.
Pengxia LiuSchool of Life Science, Inner Mongolia University, Hohhot, Inner, China.
Changshan WangSchool of Life Science, Inner Mongolia University, Hohhot, Inner, China.
Inner Mongolia University · CNInner Mongolia Medical University · CNInner Mongolia University for Nationalities · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver injury from any number of causes (e.g. chemical material, drugs and diet, viral infection) is a global health problem, and its mechanism is not clearly understood. MicroRNAs (miRNAs) expression profiling is gaining popularity because miRNAs, as key regulators in gene expression networks, can influence many biological processes and have also shown promise as biomarkers for disease. Previous studies reported the regulation effects of miRNAs in liver injury, whereas function and molecular mechanisms of miR-322-5p were still unclear. Therefore, our study focused on the biological role of miR-322-5p in carbon tetrachloride (CCl

Indexed as

Chemical and Drug Induced Liver Injury, ChronicMicroRNAsAnimalsApoptosisCarbon TetrachlorideCell CycleCell DivisionCell Line, TumorCell ProliferationGene Expression Regulation, NeoplasticMiceCarbon TetrachlorideMicroRNAsMIRN322 microRNA, mousecell cycleMiR-322-5pWee1

Identifiers

PMID35957539
PMCPMC9704413
OpenAlexW4291124190

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.