Evidence map›Paper›PMID 35957875›Full record

ArticleFrontiers in oncology2022

CEMIP Promotes Osteosarcoma Progression and Metastasis Through Activating Notch Signaling Pathway.

Jun Cheng, Yan Zhang, Rongjun Wan, Jun Zhou, Xin Wu, Qizhi Fan, Jingpeng He, Wei Tan, Youwen Deng

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 26 citations in OpenAlex.

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  10. Deciphering the Signaling Mechanisms of Osteosarcoma Tumorigenesis.International journal of molecular sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Jun ChengDepartment of Spine Surgery, The Third Xiangya Hospital, Central South University, Changsha, China.
Yan ZhangDepartment of Respiratory Medicine, Xiangya Hospital, Central South University, Changsha, China.
Rongjun WanDepartment of Respiratory Medicine, Xiangya Hospital, Central South University, Changsha, China.
Jun ZhouInstitute of Medical Sciences, Xiangya Hospital, Central South University, Changsha, China.
Xin WuDepartment of Spine Surgery, The Third Xiangya Hospital, Central South University, Changsha, China.
Qizhi FanDepartment of Spine Surgery, The Third Xiangya Hospital, Central South University, Changsha, China.
Jingpeng HeDepartment of Spine Surgery, The Third Xiangya Hospital, Central South University, Changsha, China.
Wei TanDepartment of Spine Surgery, The Third Xiangya Hospital, Central South University, Changsha, China.
Youwen DengDepartment of Spine Surgery, The Third Xiangya Hospital, Central South University, Changsha, China.
Central South University · CNThird Xiangya Hospital · CNXiangya Hospital Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cell migration inducing protein (CEMIP) has been linked to carcinogenesis in several types of cancers. However, the role and mechanism of CEMIP in osteosarcoma remain unclear. This study investigated the role of CEMIP in the progression and metastasis of osteosarcoma, CEMIP was found to be overexpressed in osteosarcoma tissues when compared to adjacent non-tumor tissues, and its expression was positively associated with a poor prognosis in osteosarcoma patients. Silencing CEMIP decreased osteosarcoma cells proliferation, migration, and invasion, but enhanced apoptosis

Indexed as

CEMIPmetastasisnotch signaling pathwayosteosarcomaprogression

Identifiers

PMID35957875
PMCPMC9361750
OpenAlexW4288040174

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.