Evidence map›Paper›PMID 35958560›Full record

ArticleFrontiers in immunology2022

Intestinal alkaline phosphatase (IAP, IAP Enhancer) attenuates intestinal inflammation and alleviates insulin resistance.

Chenzhe Gao, Marwa Yagoub Farag Koko, Mingxing Ding, Weichen Hong, Jianping Li, Na Dong, Mizhou Hui

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Chenzhe GaoThe Laboratory of Molecular Nutrition and Immunity, Institute of Animal Nutrition, Northeast Agricultural University, Harbin, China.
Marwa Yagoub Farag KokoCollege of Food, Northeast Agricultural University, Harbin, China.
Mingxing DingChangchun Jiahe Surgery Hospital, Changchun, China.
Weichen HongThe Laboratory of Molecular Nutrition and Immunity, Institute of Animal Nutrition, Northeast Agricultural University, Harbin, China.
Jianping LiCollege of Food, Northeast Agricultural University, Harbin, China.
Na DongThe Laboratory of Molecular Nutrition and Immunity, Institute of Animal Nutrition, Northeast Agricultural University, Harbin, China.
Mizhou HuiCollege of Food, Northeast Agricultural University, Harbin, China.
Northeast Agricultural University · CNChangchun Obstetrics and Gynecology Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we investigated the effects of intestinal alkaline phosphatase (IAP) in controlled intestinal inflammation and alleviated associated insulin resistance (IR). We also explored the possible underlying molecular mechanisms, showed the preventive effect of IAP on IR

Indexed as

Alkaline PhosphataseInsulin ResistanceAnimalsInflammationLipopolysaccharidesMicePhosphatidylinositol 3-KinasesAlkaline PhosphataseLipopolysaccharidesPhosphatidylinositol 3-Kinasesadenosinedephosphorylationintestinal alkaline phosphataseintestinal inflammationlipopolysaccharidesignalling pathway

Identifiers

PMID35958560
PMCPMC9359302
OpenAlexW4287447767

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.