Evidence map›Paper›PMID 35959236›Full record

ArticleFrontiers in pain research (Lausanne, Switzerland)2022

An LPAR

Jacqueline Langedijk, Erika Ivanna Araya, Amanda Ribeiro Barroso, Dagmar Tolenaars, Marc Nazaré, Hassane Belabed, Jens Schoene, Juliana Geremias Chichorro, Ronald Oude Elferink

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pain research (Lausanne, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Jacqueline LangedijkAmsterdam University Medical Centers (UMC), Tytgat Institute for Liver and Intestinal Research, University of Amsterdam, Research Institute Amsterdam Gastroenterology, Endocrinology and Metabolism (AG&M), Amsterdam, Netherlands.
Erika Ivanna ArayaDepartment of Pharmacology, Biological Sciences Sector, Federal University of Parana, Curitiba, Brazil.
Amanda Ribeiro BarrosoDepartment of Pharmacology, Biological Sciences Sector, Federal University of Parana, Curitiba, Brazil.
Dagmar TolenaarsAmsterdam University Medical Centers (UMC), Tytgat Institute for Liver and Intestinal Research, University of Amsterdam, Research Institute Amsterdam Gastroenterology, Endocrinology and Metabolism (AG&M), Amsterdam, Netherlands.
Marc NazaréDepartments of Chemical Biology and Structural Biology, Leibniz-Forschungsinstitut für Molekulare Pharmakologie, Berlin, Germany.
Hassane BelabedDepartments of Chemical Biology and Structural Biology, Leibniz-Forschungsinstitut für Molekulare Pharmakologie, Berlin, Germany.
Jens SchoeneDepartments of Chemical Biology and Structural Biology, Leibniz-Forschungsinstitut für Molekulare Pharmakologie, Berlin, Germany.
Juliana Geremias ChichorroDepartment of Pharmacology, Biological Sciences Sector, Federal University of Parana, Curitiba, Brazil.
Ronald Oude ElferinkAmsterdam University Medical Centers (UMC), Tytgat Institute for Liver and Intestinal Research, University of Amsterdam, Research Institute Amsterdam Gastroenterology, Endocrinology and Metabolism (AG&M), Amsterdam, Netherlands.
Leibniz-Forschungsinstitut für Molekulare Pharmakologie · DEUniversidade Federal do Paraná · BRUniversity of Amsterdam · NLAmsterdam University Medical Centers · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The G-protein coupled receptor LPAR Methods: Nociceptive behavior in wild type mice was induced by formalin, carrageenan or prostaglandin E2 (PGE Results: As expected, nociceptive behavior (induced by formalin, carrageenan or PGE Conclusions: Cpd3 has

Indexed as

compound 3hyperalgesiainflammatory painitch (pruritus)LPAR5nociceptionTRPA1 (transient receptor potential A1)

Identifiers

PMID35959236
PMCPMC9360597
OpenAlexW4287921608

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.