Evidence map›Paper›PMID 35962139›Full record

ArticleScientific reports2022

Nicotinamide mononucleotide ameliorates adriamycin-induced renal damage by epigenetically suppressing the NMN/NAD consumers mediated by Twist2.

Kazuhiro Hasegawa, Yusuke Sakamaki, Masanori Tamaki, Shu Wakino

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Integrative Approaches to Treating Cellular Senescence in Kidney Disease.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  4. Article
  5. The role of NADnpj metabolic health and disease · 2025
    Review
  6. Article
  7. The role of SIRT1 in kidney diseases.International urology and nephrology · 2025
    Review
  8. NAD deficiency contributes to progressive kidney disease in HIV-nephropathy mice.American journal of physiology. Renal physiology · 2024
    Article
  9. Review
  10. Ability of NAD and Sirt1 to epigenetically suppress albuminuria.Clinical and experimental nephrology · 2024
    Review
  11. Review
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Kazuhiro HasegawaDepartment of Nephrology, Tokushima University Graduate School of Biomedical Sciences, 3-18-15 Kuramoto-cho, Tokushima, 770-8503, Japan. kazuhiro@tokushima-u.ac.jp.
Yusuke SakamakiDepartment of Internal Medicine, Tokyo Dental College Ichikawa General Hospital, Chiba, 272-8583, Japan.
Masanori TamakiDepartment of Nephrology, Tokushima University Graduate School of Biomedical Sciences, 3-18-15 Kuramoto-cho, Tokushima, 770-8503, Japan.
Shu WakinoDepartment of Nephrology, Tokushima University Graduate School of Biomedical Sciences, 3-18-15 Kuramoto-cho, Tokushima, 770-8503, Japan.
Tokushima University · JPTokyo Dental College Ichikawa General Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The activation of nicotinamide adenine dinucleotide (NAD

Indexed as

Glomerulosclerosis, Focal SegmentalNicotinamide-Nucleotide AdenylyltransferaseAnimalsDoxorubicinKidneyMiceNADNicotinamide MononucleotideSirtuin 1DoxorubicinNADNicotinamide MononucleotideNicotinamide-Nucleotide AdenylyltransferaseNmnat1 protein, mouseSirtuin 1

Identifiers

PMID35962139
PMCPMC9374671
OpenAlexW4291144660

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.