Evidence map›Paper›PMID 35967117›Full record

ArticleKidney international reports2022

Phenome-Wide Association Study of

Elvis A Akwo, Hua-Chang Chen, Ge Liu, Jefferson L Triozzi, Ran Tao, Zhihong Yu, Cecilia P Chung, Ayush Giri, T Alp Ikizler, C Michael Stein and 5 more

Open access · goldAbstract read
In one paragraph

Article in Kidney international reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. A Multiomics Study of Circulating Proteins and Kidney Stone Risk.Journal of the American Society of Nephrology : JASN · 2025
    Article
  5. Review
  6. Review
  7. Insights into Uromodulin and Blood Pressure.Current hypertension reports · 2024
    Review
  8. Kidney international reports · 2024
    Article
  9. Association between Kidney Stones and CKD: A Bidirectional Mendelian Randomization Study.Journal of the American Society of Nephrology : JASN · 2024
    Article
  10. Uromodulin biology.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Elvis A AkwoDivision of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Hua-Chang ChenDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Ge LiuDepartment of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Jefferson L TriozziDivision of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Ran TaoDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Zhihong YuDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Cecilia P ChungVA Tennessee Valley Healthcare System, Nashville, Tennessee, USA.
Ayush GiriVanderbilt Genetics Institute, Nashville, Tennessee, USA.
T Alp IkizlerDivision of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
C Michael SteinDivision of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Edward D SiewDivision of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
QiPing FengDivision of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Cassianne Robinson-CohenDivision of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Adriana M HungDivision of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
VA Million Veteran Program
Vanderbilt University Medical Center · USVA Tennessee Valley Healthcare System · USVanderbilt Health · US

Funding

CSRD VA I01 CX001897
6 · The paper itself

Abstract

Introduction: Common variants in the Methods: We tested associations between Results: Among 648,593 veterans, mean (SD) age was 62 (14) years; 9% were female, 19% Black, and 8% Hispanic. In White patients, the rs4293393 Conclusion: Robust associations were observed between

Indexed as

genetic renal diseasehypertensionkidney stonesmultiethnicurinary tract infectionuromodulin

Identifiers

PMID35967117
PMCPMC9366371
OpenAlexW4280535272

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.