Evidence map›Paper›PMID 35967121›Full record

ReviewKidney international reports2022

The Evolving Role of Diagnostic Genomics in Kidney Transplantation.

Jacqueline Soraru, Aron Chakera, Nikky Isbel, Amali Mallawaarachichi, Natasha Rogers, Peter Trnka, Chirag Patel, Andrew J Mallett

Open access · goldAbstract readReview
In one paragraph

Review in Kidney international reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Advancing Genetic Testing in Kidney Diseases: Report From a National Kidney Foundation Working Group.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2024
    Review
  9. The Role of Genetic Testing in Adult CKD.Journal of the American Society of Nephrology : JASN · 2024
    Article
  10. Review
  11. Monogenic Kidney Diseases in Kidney Transplantation.Kidney international reports · 2024
    Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 1 country.

Jacqueline SoraruDepartment of Nephrology and Hypertension, Perth Children's Hospital, Perth, Western Australia, Australia.
Aron ChakeraDepartment of Renal Medicine and Transplantation, Sir Charles Gairdner Hospital, Perth, Western Australia, Australia.
Nikky IsbelDepartment of Nephrology and Transplantation, Princess Alexandra Hospital, Brisbane, Queensland, Australia.
Amali MallawaarachichiDepartment of Renal Medicine, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.
Natasha RogersDepartment of Renal Medicine and Transplantation, Westmead Hospital, Westmead, New South Wales, Australia.
Peter TrnkaChild and Adolescent Renal Service, Children's Health Queensland, Brisbane, Queensland, Australia.
Chirag PatelGenetic Health Queensland, Royal Brisbane Women's Hospital, Brisbane, Queensland, Australia.
Andrew J MallettFaculty of Medicine, The University of Queensland, Herston, Queensland, Australia.
The University of Queensland · AUGarvan Institute of Medical Research · AUHarry Perkins Institute of Medical Research · AUPrincess Margaret Hospital for Children · AURoyal Brisbane and Women's Hospital · AUTranslational Research Institute · AUWestmead Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Monogenic forms of heritable kidney disease account for a significant proportion of chronic kidney disease (CKD) across both pediatric and adult patient populations and up to 11% of patients under 40 years reaching end-stage kidney failure (KF) and awaiting kidney transplant. Diagnostic genomics in the field of nephrology is ever evolving and now plays an important role in assessment and management of kidney transplant recipients and their related donor pairs. Genomic testing can help identify the cause of KF in kidney transplant recipients and assist in prognostication around graft survival and rate of recurrence of primary kidney disease. If a gene variant has been identified in the recipient, at-risk related donors can be assessed for the same and excluded if affected. This paper aims to address the indications for genomic testing in the context for kidney transplantation, the technologies available for testing, the conditions and groups in which testing should be most often considered, and the role for the renal genetics multidisciplinary team in this process.

Indexed as

diagnostic genomicsgenetic kidney diseasekidney transplantwhole exome sequencingwhole genome sequencing

Identifiers

PMID35967121
PMCPMC9366366
OpenAlexW4281480986

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.