ArticleFrontiers in public health2022
Assessing volatile organic compounds exposure and prostate-specific antigen: National Health and Nutrition Examination Survey, 2001-2010.
Article in Frontiers in public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 18 citations in OpenAlex.
- Mediating role of chronic inflammatory airway diseases in the association between volatile organic compounds exposure and depression.Medicine · 2026Article
- Exploring the link between exposure to volatile organic chemicals and incidence of infertility:A cross-sectional study.Heliyon · 2025Article
- Associations between specific volatile organic chemical exposures and cardiovascular disease risks: insights from NHANES.Frontiers in public health · 2024Article
- The exposure to volatile organic compounds associate positively with overactive bladder risk in U.S. adults: a cross-sectional study of 2007-2020 NHANES.Frontiers in public health · 2024Article
- Chloroform associated with bone mineral density and bone mineral content in adults: A population-based cross-sectional research.PloS one · 2024Article
- Unmasking the Hidden Danger: A Decade-Long Systematic Review of Case-Control Studies on Single Occupational Risks and Prostate Cancer.Life (Basel, Switzerland) · 2023Review
- The relationship between serum albumin and prostate-specific antigen: A analysis of the National Health and Nutrition Examination Survey, 2003-2010.Frontiers in public health · 2023Article
- Association between oxidative balance score and prostate specific antigen among older US adults.Frontiers in public health · 2023Article
- Multiple statistical models reveal specific volatile organic compounds affect sex hormones in American adult male: NHANES 2013-2016.Frontiers in endocrinology · 2022Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Volatile organic compounds (VOCs) are a large group of chemicals widely used in people's daily routines. Increasing evidence revealed the VOCs' accumulating toxicity. However, the VOCs toxicity in male prostate has not been reported previously. Thus, we comprehensively evaluated the association between VOCs and prostate-specific antigen (PSA). Methods: A total of 2016 subjects were included in our study from the National Health and Nutrition Examination Survey with VOCs, PSA, and other variables among U.S. average population. We constructed XGBoost Algorithm Model, Regression Model, and Generalized linear Model (GAM) to analyze the potential association. Stratified analysis was used to identify high-risk populations. Results: XGBoost Algorithm model identified blood chloroform as the most critical variable in the PSA concentration. Regression analysis suggested that blood chloroform was a positive association with PSA, which showed that environmental chloroform exposure is an independent risk factor that may cause prostate gland changes [β, (95% CI), Conclusion: This study revealed that blood chloroform was positively and independently associated with total PSA level, suggesting that long-term environmental chloroform exposure may cause changes in the prostate gland.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.