Evidence map›Paper›PMID 35969441›Full record

ReviewJMIR medical informatics2022

State-of-the-Art Deep Learning Methods on Electrocardiogram Data: Systematic Review.

Georgios Petmezas, Leandros Stefanopoulos, Vassilis Kilintzis, Andreas Tzavelis, John A Rogers, Aggelos K Katsaggelos, Nicos Maglaveras

Abstract readReview
In one paragraph

Review in JMIR medical informatics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  15. Deep learning for electrocardiogram interpretation: Bench to bedside.European journal of clinical investigation · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Georgios PetmezasLab of Computing, Medical Informatics and Biomedical-Imaging Technologies, The Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.ORCID https://orcid.org/0000-0002-3371-569X
Leandros StefanopoulosLab of Computing, Medical Informatics and Biomedical-Imaging Technologies, The Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.ORCID https://orcid.org/0000-0002-2682-5639
Vassilis KilintzisLab of Computing, Medical Informatics and Biomedical-Imaging Technologies, The Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.ORCID https://orcid.org/0000-0002-9783-6757
Andreas TzavelisDepartment of Biomedical Engineering, Northwestern University, Evanston, IL, United States.ORCID https://orcid.org/0000-0002-0750-5007
John A RogersDepartment of Material Science, Northwestern University, Evanston, IL, United States.ORCID https://orcid.org/0000-0002-2980-3961
Aggelos K KatsaggelosDepartment of Electrical and Computer Engineering, Northwestern University, Evanston, IL, United States.ORCID https://orcid.org/0000-0003-4554-0070
Nicos MaglaverasLab of Computing, Medical Informatics and Biomedical-Imaging Technologies, The Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.ORCID https://orcid.org/0000-0002-4919-0664

Funding

Skin-like, stretchable, and wearable sensors for monitoring QT interval and hemodynamic variables in Atrial FibrillationF30HL157066 · NHLBI · NORTHWESTERN UNIVERSITY · PI TZAVELIS, ANDREAS · 2021 to 2025
$246k
NHLBI NIH HHS F30 HL157066
6 · The paper itself

Abstract

backgroundElectrocardiogram (ECG) is one of the most common noninvasive diagnostic tools that can provide useful information regarding a patient's health status. Deep learning (DL) is an area of intense exploration that leads the way in most attempts to create powerful diagnostic models based on physiological signals.

objectiveThis study aimed to provide a systematic review of DL methods applied to ECG data for various clinical applications.

methodsThe PubMed search engine was systematically searched by combining "deep learning" and keywords such as "ecg," "ekg," "electrocardiogram," "electrocardiography," and "electrocardiology." Irrelevant articles were excluded from the study after screening titles and abstracts, and the remaining articles were further reviewed. The reasons for article exclusion were manuscripts written in any language other than English, absence of ECG data or DL methods involved in the study, and absence of a quantitative evaluation of the proposed approaches.

resultsWe identified 230 relevant articles published between January 2020 and December 2021 and grouped them into 6 distinct medical applications, namely, blood pressure estimation, cardiovascular disease diagnosis, ECG analysis, biometric recognition, sleep analysis, and other clinical analyses. We provide a complete account of the state-of-the-art DL strategies per the field of application, as well as major ECG data sources. We also present open research problems, such as the lack of attempts to address the issue of blood pressure variability in training data sets, and point out potential gaps in the design and implementation of DL models.

conclusionsWe expect that this review will provide insights into state-of-the-art DL methods applied to ECG data and point to future directions for research on DL to create robust models that can assist medical experts in clinical decision-making.

Indexed as

clinical decisionCNNconvolutional neural networksdecision supportdeep learningdiagnostic toolsECGECG databaseselectrocardiogramlong short-term memoryLSTMresidual neural networkResNet

Identifiers

PMID35969441
PMCPMC9425174

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.