Evidence map›Paper›PMID 35971518›Full record

ArticleComputational and structural biotechnology journal2022

Evaluation of the role of vaccination in the COVID-19 pandemic based on the data from the 50 U.S. States.

Rongfang Nie, Zeinab Abdelrahman, Zhixian Liu, Xiaosheng Wang

Open access · goldAbstract read
In one paragraph

Article in Computational and structural biotechnology journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Role of vaccine in fighting the variants of COVID-19.Chaos, solitons, and fractals · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Rongfang NieBiomedical Informatics Research Lab, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing 211198, China.
Zeinab AbdelrahmanDepartment of Neurobiology and Department of Orthopedics, 2nd Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province 310009, China.
Zhixian LiuJiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, The Affiliated Cancer Hospital of Nanjing Medical University, Nanjing 210009, China.
Xiaosheng WangBiomedical Informatics Research Lab, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing 211198, China.
China Pharmaceutical University · CNAllen Institute for Brain Science · USJiangsu Cancer Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vaccination is considered as the ultimate weapon to end the pandemic. However, the role of vaccines in the pandemic remains controversial. To explore the impact of vaccination on the COVID-19 pandemic, we used logistic regression models to predict numbers of population-adjusted confirmed cases, deaths, intensive care unit (ICU) cases, case fatality rates and ICU admission rates of COVID-19 in the 50 U.S. states, based on 17 related variables. The logistic regression analysis showed that percentages of people vaccinated correlated inversely with the numbers of COVID-19 deaths and case fatality rates but showed no significant correlation with numbers of confirmed cases or ICU cases, or ICU admission rates. The Spearman correlation analysis showed that the percentages of people vaccinated correlated inversely with the numbers of COVID-19 deaths, ICU cases, ICU case rates, and case fatality rates but showed no significant correlation with numbers of confirmed cases. The number of deaths and mortality in the group after the vaccine usage were significantly lower than those in the group before the vaccine usage. However, after delta became the dominant strain, there were no longer significant differences in the number of deaths and the mortality rate between before and after delta became the dominant strain, although vaccines were used in both periods. Vaccination can significantly reduce COVID-19 deaths and mortality, while it cannot reduce the risk of COVID-19 infection. In addition to vaccination, other measures, such as social distancing, remain important in containing COVID-19 transmission and lower the risk of COVID-19 severe outcomes.

Indexed as

AUC, The area under the receiver operating characteristic curveCDC, The Centers for Disease Control and PreventionCOVID-19COVID-19, Coronavirus disease 2019ICU, Intensive care unitMachine learningProtective and risk factorsSARS-CoV-2, Severe acute respiratory syndrome coronavirus 2VaccinationVirus variant

Identifiers

PMID35971518
PMCPMC9359589
OpenAlexW4291736609

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.