ReviewChemical Society reviews2022
Knotting matters: orderly molecular entanglements.
Review in Chemical Society reviews, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed, 132 citations in OpenAlex.
- Trefoil polymers from a knotted synthon.Nature chemistry · 2026Article
- Efficient synthesis of complex supramolecular topologies via coordination angle modulation.National science review · 2026Article
- Tangled Tail of Mechanically Interlocked Peptides.Journal of the American Chemical Society · 2026Review
- Article
- Single-molecule magnetic tweezers reveal distinct dynamics and enhanced mechanical stability of ssDNA 31 and 52 knots.Nucleic acids research · 2026Article
- Robust chirality-induced spin selectivity in topologically chiral molecular knots.Nature communications · 2025Article
- Revealing the topological nature of entangled orbital angular momentum states of light.Nature communications · 2025Article
- Design and Structural Transformations of Zinc(II) Knotted Cage Frameworks.Angewandte Chemie (International ed. in English) · 2025Article
- Enabling technology for accelerated discovery of supramolecular materials.Chemical science · 2025Review
- Novel metallo-supramolecular architectures based on side-pyridine-modified terpyridines: design, self-assembly, and properties.Chemical science · 2025Review
- Effective RNA Complexation by [2]Catenanes Confers Enhanced Resistance to Enzymatic Degradation.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Article
- Modulation of Lanthanide Luminescence with the Mechanical Bond: Antenna-Emitter Confinement in a Compact [2]Rotaxane.Angewandte Chemie (International ed. in English) · 2025Article
- Emerging mechanically interlocked cages.Nature reviews. Chemistry · 2025Review
- The Flexibility of Tetra(N-Heterocyclic Carbene) Ligands Controls the Nuclearity and Geometry of Polynuclear MAngewandte Chemie (International ed. in English) · 2025Article
- Step-by-Step Self-Assembly of a Double-Walled Knotted Cage With Increasing Topological Complexity.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Article
- Self-assembly, interlocking, interconversion and anion-binding catalysis in phenoxazine-based PdNature communications · 2025Article
- Article
- Synthesis of covalently linked knotted cage frameworks.Nature synthesis · 2025Article
- Phosphorescent metallaknots of Au(I)-bis(acetylide) strands directed by Cu(I) π-coordination.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Folding a Molecular Strand into a Trefoil Knot of Single Handedness with Co(II)/Co(III) Chaperones.Journal of the American Chemical Society · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Entangling strands in a well-ordered manner can produce useful effects, from shoelaces and fishing nets to brown paper packages tied up with strings. At the nanoscale, non-crystalline polymer chains of sufficient length and flexibility randomly form tangled mixtures containing open knots of different sizes, shapes and complexity. However, discrete molecular knots of precise topology can also be obtained by controlling the number, sequence and stereochemistry of strand crossings: orderly molecular entanglements. During the last decade, substantial progress in the nascent field of molecular nanotopology has been made, with general synthetic strategies and new knotting motifs introduced, along with insights into the properties and functions of ordered tangle sequences. Conformational restrictions imparted by knotting can induce allostery, strong and selective anion binding, catalytic activity, lead to effective chiral expression across length scales, binding modes in conformations efficacious for drug delivery, and facilitate mechanical function at the molecular level. As complex molecular topologies become increasingly synthetically accessible they have the potential to play a significant role in molecular and materials design strategies. We highlight particular examples of molecular knots to illustrate why these are a few of our favourite things.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.