Evidence map›Paper›PMID 35983626›Full record

ReviewCNS neuroscience & therapeutics2022

Relationship between chronic hypoxia and seizure susceptibility.

YuanHang Xu, QingLi Fan

Open access · goldAbstract readReview
In one paragraph

Review in CNS neuroscience & therapeutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 30 citations in OpenAlex.

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  9. [Amplitude-integrated electroencephalography monitoring results of hospitalized neonates in plateau areas].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

YuanHang XuQinghai University Graduate School, Xining, China.ORCID 0000-0002-4539-0650
QingLi FanDepartment of Neurology, Qinghai Provincial People's Hospital Xining, Xining, China.
Qinghai Provincial Peoples Hospital · CNQinghai University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic hypobaric hypoxia in high-altitude areas is closely related to the occurrence of many neurological diseases. Among these diseases, epilepsy is a common disease of the nervous system that is difficult to diagnose and treat, with a long treatment cycle. As of 2019, there were more than 70 million epilepsy patients worldwide, including 10 million in China. Studies have shown that chronic hypoxia promotes the occurrence and development of epilepsy, and elucidation of the relationship between chronic hypoxia and epilepsy is important for studying the pathogenesis of epilepsy and exploring the potential characteristics of epilepsy and new drug targets for epilepsy. In this article, we review the factors that may cause increased seizure susceptibility in chronic hypoxia and consider the potential relationship between chronic hypobaric hypoxia and seizure susceptibility in high-altitude areas and prospects surrounding related research in the future.

Indexed as

EpilepsyHypoxiaChinaHumansSeizuresAQP4brain-derived neurotrophic factorcerebral blood flowchronic hypoxiaglial cellshigh altitudehypothalamus-pituitary-adrenal axisneuroinflammationneurosteroidsoxidative stressseizure susceptibilitysodium potassium ATPasestressWnt/β-catenin

Identifiers

PMID35983626
PMCPMC9532927
OpenAlexW4292373367

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.