ReviewThe Lancet. Respiratory medicine2022
Tobacco product use and the risks of SARS-CoV-2 infection and COVID-19: current understanding and recommendations for future research.
Review in The Lancet. Respiratory medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
51 citing papers in PubMed, 74 citations in OpenAlex.
- Article
- COVID-19 symptoms associated with smoking and vaping tobacco and cannabis: A cross-sectional analysis.Preventive medicine reports · 2025Article
- Adolescents' Interest in Quitting Nicotine or Cannabis E-Cigarettes.Clinical pediatrics · 2025Article
- COVID-19 Disease and Chronic Health Outcomes Associated with Nicotine Use in a Great Plains Tribal Community: A Community-Based Study.Journal of racial and ethnic health disparities · 2025Article
- Survival and transmission fitness of SARS-CoV-2 over the time-of-flight in an aerosolization chamber.Npj viruses · 2025Article
- Impact of the COVID-19 Pandemic on Changes in Tobacco Use Behavior: A Longitudinal Cohort Study in Japan.Journal of epidemiology · 2025Article
- Contextualizing Changes in e-Cigarette Use During the Early COVID-19 Pandemic and Accompanying Infodemic ("So Much Contradictory Evidence"): Qualitative Document Analysis of Reddit Forums.Journal of medical Internet research · 2025Article
- Research prioritisation in preparedness for and response to outbreaks of high-consequence pathogens: a scoping review.BMC medicine · 2025Article
- Estimating the association between cigarette and e-cigarette use patterns and SARS-CoV-2 negative conversion time: retrospective online survey in China.BMC infectious diseases · 2025Article
- Clinical outcomes of COVID-19 in patients with liver cirrhosis - a propensity-matched analysis from a multicentric Brazilian cohort.BMC infectious diseases · 2025Article
- Association between long-term smoking cessation and COVID-19 outcomes: Findings from a nationwide crosssectional online survey in China.Tobacco induced diseases · 2025Article
- The problem of frailty caused by acute infection and future health management strategies to improve frailty.Frontiers in public health · 2025Article
- COVID-19 Vaccine Acceptance among People who Smoke in Rural Southwest Georgia: Perspectives and Influencing Factors.Journal of the Georgia Public Health Association · 2025Article
- What Is the Real Impact of Smoking on Diseases Alleged to Benefit from It?European addiction research · 2025Review
- Environmental Risk Factors for Acute Respiratory Distress Syndrome.Clinics in chest medicine · 2024Review
- Identification of Biomarkers and Molecular Pathways Implicated in Smoking and COVID-19 Associated Lung Cancer Using Bioinformatics and Machine Learning Approaches.International journal of environmental research and public health · 2024Article
- Social Media Exposure and Other Correlates of Increased e-Cigarette Use Among Adolescents During Remote Schooling: Cross-Sectional Study.JMIR pediatrics and parenting · 2024Article
- Acute and long COVID-19 symptoms and associated factors in the omicron-dominant period: a nationwide survey via the online platform Wenjuanxing in China.BMC public health · 2024Article
- Design, Synthesis, and Structure-Activity Relationships of Novel Peptide Derivatives of the Severe Acute Respiratory Syndrome-Coronavirus-2 Spike-Protein that Potently Inhibit Nicotinic Acetylcholine Receptors.Journal of medicinal chemistry · 2024Article
- Engagement, Mental Health, and Substance Use Under In-Person or Remote School Instruction During the COVID-19 Pandemic.The Journal of school health · 2024Article
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Authors and funding
9 authors at 6 institutions in 1 country.
Funding
Abstract
Heterogeneity in the clinical presentation of SARS-CoV-2 infection and COVID-19 progression underscores the urgent need to identify individual-level susceptibility factors that affect infection vulnerability and disease severity. Tobacco product use is a potential susceptibility factor. In this Personal View, we provide an overview of the findings of peer-reviewed, published studies relating tobacco product use to SARS-CoV-2 infection and COVID-19 outcomes, with most studies focusing on cigarette smoking in adults. Findings pertaining to the effects of tobacco product use on the incidence of SARS-CoV-2 infection are inconsistent. However, evidence supports a role for cigarette smoking in increasing the risk of poor COVID-19 outcomes, including hospital admission, progression in disease severity, and COVID-19-related mortality. We discuss the potential effects of tobacco use behaviour on SARS-CoV-2 transmission and infection, and highlight the pathophysiological changes associated with cigarette smoking that could promote SARS-CoV-2 infection and increased disease severity. We consider the biological mechanisms by which nicotine and other tobacco product constituents might affect immune and inflammatory responses to SARS-CoV-2 infection. Finally, we identify current knowledge gaps and suggest priorities for research to address acute and post-acute health outcomes of COVID-19 during and after the pandemic.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.