Evidence map›Paper›PMID 35986498›Full record

ArticlePhysiological reports2022

Efficacy of interval exercise training to improve vascular health in sedentary postmenopausal females.

Gemma K Lyall, Gurpreet K Birk, Emma Harris, Carrie Ferguson, Kirsten Riches-Suman, Mark T Kearney, Karen E Porter, Karen M Birch

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Rates of compliance and adherence to high-intensity interval training: a systematic review and Meta-analyses.The international journal of behavioral nutrition and physical activity · 2023
    Pooled it
  3. The Time Course of Cardiorespiratory Adaptations to Rowing Indoor Training in Post-Menopausal Women.International journal of environmental research and public health · 2023
    Trial
  4. Effects of regular exercise on vascular function with aging: Does sex matter?American journal of physiology. Heart and circulatory physiology · 2024
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Gemma K LyallSchool of Biomedical Sciences, Faculty of Biological Sciences and Multidisciplinary, Cardiovascular Research Centre, University of Leeds, Leeds, UK.
Gurpreet K BirkIVS Ltd, Vascular Ultrasound, Royal Oldham Hospital, Oldham, UK.
Emma HarrisSchool of Human and Health Sciences, Centre for Applied Research in Health, University of Huddersfield, Huddersfield, UK.
Carrie FergusonInstitute of Respiratory Medicine and Exercise Physiology, Rehabilitation Clinical Trials Center, Division of Respiratory and Critical Care Physiology and Medicine, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California, USA.
Kirsten Riches-SumanSchool of Chemistry and Biosciences, University of Bradford, Bradford, UK.
Mark T KearneyLeeds Institute of Cardiovascular and Metabolic Medicine & Multidisciplinary, Cardiovascular Research Centre, University of Leeds, Leeds, UK.
Karen E PorterLeeds Institute of Cardiovascular and Metabolic Medicine & Multidisciplinary, Cardiovascular Research Centre, University of Leeds, Leeds, UK.
Karen M BirchSchool of Biomedical Sciences, Faculty of Biological Sciences and Multidisciplinary, Cardiovascular Research Centre, University of Leeds, Leeds, UK.ORCID 0000-0001-7796-8640
University of Leeds · GBLeeds General Infirmary · GBUCLA Medical Center · USUniversity of Bradford · GBUniversity of Huddersfield · GB

Funding

British Heart Foundation CH/13/1/30086
6 · The paper itself

Abstract

backgroundMenopause represents a turning point where vascular damage begins to outweigh reparative processes, leading to increased cardiovascular disease (CVD) risk. Exercise training reduces CVD risk in postmenopausal females via improvements in traditional risk factors and direct changes to the vasculature. We assessed the effect of moderate (MODERATE-IT) versus heavy (HEAVY-IT) intensity interval exercise training upon markers of cardiovascular health and vascular repair in postmenopausal females.

methodsTwenty-seven healthy postmenopausal females (56 ± 4 yr) were assigned to 12 weeks of either MODERATE-IT or HEAVY-IT, twice per week. MODERATE-IT consisted of 10s work, and 10s active recovery repeated for 30 min. HEAVY-IT comprised 30s work, and 30s active recovery repeated for 21 ± 2 min. Endothelial function (flow-mediated dilation), arterial stiffness (pulse wave velocity), and V̇O

resultsV̇O

conclusionsHEAVY-IT was more effective at increasing V̇O

Indexed as

Cardiovascular DiseasesVascular StiffnessEndothelium, VascularExerciseFemaleHumansPostmenopausePulse Wave Analysiscirculating angiogenic cellsendothelial functioninterval exercisepostmenopausal femalesV̇O2peak

Identifiers

PMID35986498
PMCPMC9391601
OpenAlexW4292854798

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.