ArticleBMC cardiovascular disorders2022
Impact of estimated glucose disposal rate for identifying prevalent ischemic heart disease: findings from a cross-sectional study.
Article in BMC cardiovascular disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 27 citations in OpenAlex.
- Estimated glucose disposal rate (eGDR) predicts rehospitalization & death in acute decompensated heart failure in the elderly.Heart and vessels · 2026Article
- Risk Prediction of Edentulism in Chinese Adults: Insights From the China Health and Retirement Longitudinal Study (CHARLS).International dental journal · 2026Article
- Association between the cumulative estimated glucose disposal rate and incident stroke in adults aged 50 and above without diabetes: a prospective nationwide cohort study in China.Cardiovascular diabetology · 2025Article
- Association between estimated glucose disposal rate and testosterone deficiency in male patients with type 2 diabetes mellitus.BMC endocrine disorders · 2025Article
- Association between estimated glucose disposal rate and heart failure in patients with diabetes or prediabetes: a cross-sectional study.BMC public health · 2025Article
- Influence of metabolism-related comorbidities and insulin resistance on new onset of chronic kidney disease in a health check-up population: a two-stage retrospective cohort study.BMJ open diabetes research & care · 2025Article
- Insulin resistance quantified by estimated glucose disposal rate predicts cardiovascular disease incidence: a nationwide prospective cohort study.Cardiovascular diabetology · 2025Article
- Association between the cumulative estimated glucose disposal rate and incident cardiovascular disease in individuals over the age of 50 years and without diabetes: data from two large cohorts in China and the United States.Cardiovascular diabetology · 2025Article
- Correlation between estimated glucose disposal rate, insulin resistance, and cardiovascular mortality among individuals with metabolic syndrome: a population-based analysis, evidence from NHANES 1999-2018.Diabetology & metabolic syndrome · 2025Article
- Correlation between estimated glucose disposal rate and diabetic depression: a population-based study.Frontiers in psychiatry · 2025Article
- The Relationship of Insulin Resistance and Systemic Inflammation with Cardiovascular Outcomes in Non-Diabetic Patients Undergoing Coronary Artery Bypass Grafting.Journal of inflammation research · 2025Article
- Linking Estimated Glucose Disposal Rate to Major Adverse Cardio-Cerebrovascular Events in Populations With and Without Diabetes: A Systematic Review and Meta-Analysis.Clinical medicine insights. Endocrinology and diabetes · 2025Article
- Estimated glucose disposal rate is correlated with increased depression: a population-based study.BMC psychiatry · 2024Article
- Estimated glucose disposal rate and risk of cardiovascular disease and mortality in U.S. adults with prediabetes: a nationwide cross-sectional and prospective cohort study.Acta diabetologica · 2024Article
- Association of estimated glucose disposal rate with incident cardiovascular disease under different metabolic and circadian rhythm states: findings from a national population-based prospective cohort study.Diabetology & metabolic syndrome · 2024Article
- Usefulness of estimated glucose disposal rate in detecting heart failure: results from national health and nutrition examination survey 1999-2018.Diabetology & metabolic syndrome · 2024Article
- Evaluation of Estimated Glucose Disposal Rate with Neutrophil-to-Lymphocyte Ratio Integrated for Prognosticating Adverse Cardiovascular and Cerebrovascular Events and Risk Stratification Among Acute Coronary Syndrome with Type 2 Diabetes Mellitus Following Percutaneous Coronary Intervention.Journal of inflammation research · 2024Article
- Assessment of Various Insulin Resistance Surrogate Indices in Thai People with Type 2 Diabetes Mellitus.Journal of the ASEAN Federation of Endocrine Societies · 2024Article
- Estimated glucose disposal rate and risk of cardiovascular disease: evidence from the China Health and Retirement Longitudinal Study.BMC geriatrics · 2022Article
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInsulin resistance is one of the major mechanisms for cardiovascular events. Estimated glucose disposal rate(eGDR) has been demonstrated as a simple, accurate, and cost-effective estimator of insulin resistance. Our study aims to evaluate the correlation between eGDR and the prevalent IHD and assess the incremental value of eGDR for identifying prevalent IHD in the rural general population.
methodsOur study enrolled 10,895 participants from a cross-sectional survey of a metabolic management program. The survey was conducted in the rural areas of southeastern China between October 2019 and April 2020. eGDR = 21.158 - (0.09 * waist circumference) - (3.407 * hypertension) - (0.551 * HbA1c).
resultsThe prevalence of IHD was 4.20%. After adjusting for demographic, anthropometric, laboratory, and medical history covariates, each SD increase of eGDR brought a 25.9% risk reduction for prevalent IHD. After dividing eGDR into groups, the top group had a 58.9% risk reduction than the bottom group. Furthermore, smooth curve fitting demonstrated that the correlation between eGDR and prevalent IHD was linear in the whole range of eGDR. Additionally, AUC suggested that eGDR could significantly improve the identification of prevalent IHD by adding it to cardiovascular risk factors (0.703 vs. 0.711, P for comparison = 0.041). Finally, the category-free net reclassification index and integrated discrimination index also implicated the improvement from eGDR to identify prevalent IHD.
conclusionOur data demonstrated a significant, negative, and linear correlation between eGDR and prevalent IHD. Our findings could suggest the potential usefulness of eGDR to improve the identification of prevalent IHD in the rural general population.
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