Evidence map›Paper›PMID 35999686›Full record

ReviewJournal of diabetes2022

Glomerular cell cross talk in diabetic kidney diseases.

Ruixue Dong, Youhua Xu

Open access · goldAbstract readReview
In one paragraph

Review in Journal of diabetes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

Ruixue DongFaculty of Pharmacy, Macau University of Science and Technology, Taipa, Macau, People's Republic of China.ORCID https://orcid.org/0000-0002-5459-9624
Youhua XuFaculty of Pharmacy, Macau University of Science and Technology, Taipa, Macau, People's Republic of China.
Macau University of Science and Technology · MO

Funding

The Science and Technology Development Fund of Macau 0055/2019/AMJ
6 · The paper itself

Abstract

Diabetic kidney disease (DKD) is a severe microvascular complication of diabetes mellitus. It is the leading inducement of end-stage renal disease (ESRD), and its global incidence has been increasing at an alarming rate. The strict control of blood pressure and blood glucose can delay the progression of DKD, but intensive treatment is challenging to maintain. Studies to date have failed to find a complete cure. The glomerulus's alterations and injuries play a pivotal role in the initiation and development of DKD. A wealth of data indicates that the interdependent relationship between resident cells in the glomerulus will provide clues to the mechanism of DKD and new ways for therapeutic intervention. This review summarizes the significant findings of glomerular cell cross talk in DKD, focusing on cellular signaling pathways, regulators, and potential novel avenues for treating progressive DKD.

Indexed as

Diabetes MellitusDiabetic NephropathiesKidney Failure, ChronicBlood GlucoseBlood PressureHumansKidneyKidney GlomerulusBlood Glucosecell cross talkdiabetic kidney diseaseglomerulus糖尿病肾病细胞相互作用肾小球

Identifiers

PMID35999686
PMCPMC9426281
OpenAlexW4293163585

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.