Evidence map›Paper›PMID 36005175›Full record

ArticleCurrent oncology (Toronto, Ont.)2022

The Effect of Tobacco Smoke

Sotirios G Doukas, Dimitra P Vageli, Panagiotis G Doukas, Dragana Nikitovic, Aristidis Tsatsakis, Benjamin L Judson

Open access · goldAbstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Cell signaling and epigenetic regulation of nicotine-induced carcinogenesis.Environmental pollution (Barking, Essex : 1987) · 2024
    Review
  8. Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Sotirios G DoukasThe Yale Larynx Laboratory, Department of Surgery, Yale School of Medicine, New Haven, CT 06510, USA.
Dimitra P VageliThe Yale Larynx Laboratory, Department of Surgery, Yale School of Medicine, New Haven, CT 06510, USA.ORCID 0000-0002-9852-5790
Panagiotis G DoukasThe Yale Larynx Laboratory, Department of Surgery, Yale School of Medicine, New Haven, CT 06510, USA.ORCID 0000-0001-8050-963X
Dragana NikitovicDepartment of Histology & Embryology, Medical School, University of Crete, 71003 Heraklion, Greece.ORCID 0000-0003-3882-7399
Aristidis TsatsakisDepartment of Forensic Sciences and Laboratory of Toxicology, Medical School, University of Crete, 71003 Heraklion, Greece.ORCID 0000-0003-3824-2462
Benjamin L JudsonThe Yale Larynx Laboratory, Department of Surgery, Yale School of Medicine, New Haven, CT 06510, USA.
University of Crete · GRRutgers, The State University of New Jersey · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

Deregulation of the DNA mismatch repair (MMR) mechanism has been linked to poor prognosis of upper aerodigestive tract cancers. Our recent in vitro data have provided evidence of crosstalk between deregulated miRNAs and MMR genes, caused by tobacco smoke (TS)

Indexed as

Head and Neck NeoplasmsMicroRNAsNitrosaminesTobacco Smoke PollutionCarcinogensDNA Mismatch RepairHumansNicotineSmokeSquamous Cell Carcinoma of Head and NeckCarcinogensMicroRNAsNicotineNitrosaminesSmokeTobacco Smoke PollutionDNA mismatch repairhead and neck cancerhuman hypopharyngeal squamous cell carcinomaMLH1MSH2NDEAnicotineN-NitrosaminesNNKtobacco smoke

Identifiers

PMID36005175
PMCPMC9406897
OpenAlexW4289986017

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.