Evidence mapPaperPMID 36008559Full record

SynthesisDiabetologia2022

Nordic dietary patterns and cardiometabolic outcomes: a systematic review and meta-analysis of prospective cohort studies and randomised controlled trials.

Paraskevi Massara, Andreea Zurbau, Andrea J Glenn, Laura Chiavaroli, Tauseef A Khan, Effie Viguiliouk, Sonia Blanco Mejia, Elena M Comelli, Victoria Chen, Ursula Schwab and 10 more

Registry-linked trialOpen access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Diabetologia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04094194 (Relation of the Nordic Dietary Pattern With Cardiometabolic Risk Factors and Incident Cardiovascular Outcomes), which is not on this map. Cited by 29 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 6 pooled it
9.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04094194 unknown statusnot on this map

Relation of the Nordic Dietary Pattern With Cardiometabolic Risk Factors and Incident Cardiovascular Outcomes: A Systematic Review and Meta-analysis of Randomized Controlled Trials and Prospective Cohort Studies

TypeobservationalSponsorUniversity of TorontoRan2017 to 2019Enrolled1ConditionsBody Weight, Obesity, Overweight and Obesity, Obesity, AbdominalArmsNordic diet
3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 6 syntheses or guidelines pooled it, 50 citations in OpenAlex.

  1. Pooled it
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  10. Article
  11. Nutrition Strategies for Next-Generation Incretin Therapies: A Systematic Scoping Review of the Current Evidence.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
    Article
  12. Article
  13. Review
  14. Nutrition and longevity - diet in centenarians.Journal of translational medicine · 2026
    Review
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  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 10 institutions in 10 countries.

Paraskevi MassaraDepartment of Nutritional Sciences, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.ORCID 0000-0003-0906-0985
Andreea ZurbauDepartment of Nutritional Sciences, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.ORCID 0000-0003-2927-3689
Andrea J GlennDepartment of Nutritional Sciences, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.ORCID 0000-0002-9302-2676
Laura ChiavaroliDepartment of Nutritional Sciences, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Tauseef A KhanDepartment of Nutritional Sciences, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.ORCID 0000-0002-3713-2248
Effie ViguilioukDepartment of Nutritional Sciences, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Sonia Blanco MejiaDepartment of Nutritional Sciences, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.ORCID 0000-0003-4199-1800
Elena M ComelliDepartment of Nutritional Sciences, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.ORCID 0000-0002-5201-5437
Victoria ChenDepartment of Nutritional Sciences, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Ursula SchwabInstitute of Public Health and Clinical Nutrition, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland. ursula.schwab@uef.fi.ORCID 0000-0003-1838-7525
Ulf RisérusDepartment of Public Health and Caring Sciences, Clinical Nutrition and Metabolism, Uppsala University, Uppsala, Sweden.ORCID 0000-0002-8620-4586
Matti UusitupaInstitute of Public Health and Clinical Nutrition, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland.
Anne-Marie AasDivision of Medicine, Department of Clinical Service, Section of Nutrition and Dietetics, Oslo University Hospital, Oslo, Norway.
Kjeld HermansenDepartment of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark.
Inga ThorsdottirUnit for Nutrition Research, Health Science Institute, University of Iceland, Reykjavík, Iceland.
Dario RahelićVuk Vrhovac University Clinic for Diabetes, Endocrinology and Metabolic Diseases, Merkur University Hospital, Zagreb, Croatia.
Hana KahleováInstitute for Clinical and Experimental Medicine, Diabetes Centre, Prague, Czech Republic.ORCID 0000-0003-0491-3993
Jordi Salas-SalvadóCentro de Investigacion Biomedica en Red de Fisiopatología de la Obesidad y Nutrición (CIBERObn), Instituto de Salud Carlos III, Madrid, Spain.
Cyril W C KendallDepartment of Nutritional Sciences, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
John L SievenpiperDepartment of Nutritional Sciences, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada. john.sievenpiper@utoronto.ca.ORCID 0000-0002-3270-5772
St. Michael's Hospital · CAUniversity of Toronto · CAUniversity of Eastern Finland · FIAarhus University · DKCatholic University of Croatia · HRInstituto de Salud Carlos III · ESOslo University Hospital · NOPhysicians Committee for Responsible Medicine · USUniversity of Iceland · ISUppsala University · SE

Funding

CIHR 129920
6 · The paper itself

Abstract

aims/hypothesisNordic dietary patterns that are high in healthy traditional Nordic foods may have a role in the prevention and management of diabetes. To inform the update of the EASD clinical practice guidelines for nutrition therapy, we conducted a systematic review and meta-analysis of Nordic dietary patterns and cardiometabolic outcomes.

methodsWe searched MEDLINE, EMBASE and The Cochrane Library from inception to 9 March 2021. We included prospective cohort studies and RCTs with a follow-up of ≥1 year and ≥3 weeks, respectively. Two independent reviewers extracted relevant data and assessed the risk of bias (Newcastle-Ottawa Scale and Cochrane risk of bias tool). The primary outcome was total CVD incidence in the prospective cohort studies and LDL-cholesterol in the RCTs. Secondary outcomes in the prospective cohort studies were CVD mortality, CHD incidence and mortality, stroke incidence and mortality, and type 2 diabetes incidence; in the RCTs, secondary outcomes were other established lipid targets (non-HDL-cholesterol, apolipoprotein B, HDL-cholesterol, triglycerides), markers of glycaemic control (HbA

resultsWe included 15 unique prospective cohort studies (n=1,057,176, with 41,708 cardiovascular events and 13,121 diabetes cases) of people with diabetes for the assessment of cardiovascular outcomes or people without diabetes for the assessment of diabetes incidence, and six RCTs (n=717) in people with one or more risk factor for diabetes. In the prospective cohort studies, higher adherence to Nordic dietary patterns was associated with 'small important' reductions in the primary outcome, total CVD incidence (RR for highest vs lowest adherence: 0.93 [95% CI 0.88, 0.99], p=0.01; substantial heterogeneity: I CONCLUSIONS/

interpretationAdherence to Nordic dietary patterns is associated with generally small important reductions in the risk of major CVD outcomes and diabetes, which are supported by similar reductions in LDL-cholesterol and other intermediate cardiometabolic risk factors. The available evidence provides a generally good indication of the likely benefits of Nordic dietary patterns in people with or at risk for diabetes. REGISTRATION: ClinicalTrials.gov NCT04094194.

fundingDiabetes and Nutrition Study Group of the EASD Clinical Practice.

Indexed as

Cardiovascular DiseasesDiabetes Mellitus, Type 2InsulinsStrokeApolipoproteinsBody WeightCholesterolCholesterol, HDLCholesterol, LDLHumansInflammationObesityProspective StudiesRandomized Controlled Trials as TopicApolipoproteinsCholesterolCholesterol, HDLCholesterol, LDLInsulinsCardiovascular diseaseMeta-analysisNordic dietProspective cohortRandomised controlled trialSystematic review

Identifiers

PMID36008559
PMCPMC9630197
OpenAlexW4293237531

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.