Evidence mapPaperPMID 36009012Full record

Observational studyBiomolecules2022

The Role of Nutraceutical Supplements, Monacolin K and Astaxanthin, and Diet in Blood Cholesterol Homeostasis in Patients with Myopathy.

Ines Villano, Marco La Marra, Salvatore Allocca, Ciro Rosario Ilardi, Rita Polito, Chiara Porro, Sergio Chieffi, Giovanni Messina, Vincenzo Monda, Girolamo Di Maio and 1 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Biomolecules, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Ines VillanoDepartment of Experimental Medicine, Section of Human Physiology and Unit of Dietetic and Sport Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0002-1755-358X
Marco La MarraDepartment of Experimental Medicine, Section of Human Physiology and Unit of Dietetic and Sport Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0001-7488-8493
Salvatore AlloccaDepartment of Experimental Medicine, Section of Human Physiology and Unit of Dietetic and Sport Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Ciro Rosario IlardiDepartment of Psychology, University of Campania "Luigi Vanvitelli", 81100 Caserta, Italy.ORCID 0000-0003-4328-4739
Rita PolitoDepartment of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy.
Chiara PorroDepartment of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy.ORCID 0000-0002-7526-6968
Sergio ChieffiDepartment of Experimental Medicine, Section of Human Physiology and Unit of Dietetic and Sport Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Giovanni MessinaDepartment of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy.ORCID 0000-0002-0011-867X
Vincenzo MondaDepartment of Movement Sciences and Wellbeing, University of Naples "Parthenope", 80138 Naples, Italy.
Girolamo Di MaioDepartment of Experimental Medicine, Section of Human Physiology and Unit of Dietetic and Sport Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0001-6305-2092
Antonietta MessinaDepartment of Experimental Medicine, Section of Human Physiology and Unit of Dietetic and Sport Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
University of Campania "Luigi Vanvitelli" · ITUniversity of Foggia · ITParthenope University of Naples · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several studies suggest that different combinations of nutraceutical supplements may improve the lipid profile, representing a viable alternative to statins. However, their effects on individuals with myopathy need to be investigated. The aim of our study was to explore the mid- and long-term physiological effects of monacolin k (5 mg) and astaxanthin (0.1 mg) supplements in association with a low-energy/fat diet in a group of subjects with mild myopathy. Eighty subjects (44 women) took part in this observational study. Participants were assigned to the experimental group (EG,

Indexed as

LovastatinMuscular DiseasesCholesterol, HDLDietDietary SupplementsFemaleHomeostasisHumansLipidsXanthophyllsastaxanthineCholesterol, HDLLipidsLovastatinXanthophyllsantioxidantastaxanthincholesteroldietdietary supplementdyslipidemiamonacolin kmyopathy

Identifiers

PMID36009012
PMCPMC9405860
OpenAlexW4291415349

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.