Evidence map›Paper›PMID 36010882›Full record

ReviewCancers2022

BRCA Mutations in Ovarian and Prostate Cancer: Bench to Bedside.

Stergios Boussios, Elie Rassy, Michele Moschetta, Aruni Ghose, Sola Adeleke, Elisabet Sanchez, Matin Sheriff, Cyrus Chargari, Nicholas Pavlidis

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 4 pooled it
11.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 4 syntheses or guidelines pooled it, 110 citations in OpenAlex.

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  10. Identification and Computational Analysis ofMedical sciences (Basel, Switzerland) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 4 countries.

Stergios BoussiosDepartment of Medical Oncology, Medway NHS Foundation Trust, Windmill Road, Gillingham ME7 5NY, UK.ORCID 0000-0002-2512-6131
Elie RassyDepartment of Medical Oncology, Gustave Roussy Institut, 94805 Villejuif, France.ORCID 0000-0002-7906-0991
Michele MoschettaNovartis Institutes for BioMedical Research, CH 4033 Basel, Switzerland.
Aruni GhoseDepartment of Medical Oncology, Medway NHS Foundation Trust, Windmill Road, Gillingham ME7 5NY, UK.ORCID 0000-0001-8332-8033
Sola AdelekeHigh Dimensional Neurology Group, UCL Queen's Square Institute of Neurology, London WC1N 3BG, UK.ORCID 0000-0002-4388-8754
Elisabet SanchezDepartment of Medical Oncology, Medway NHS Foundation Trust, Windmill Road, Gillingham ME7 5NY, UK.
Matin SheriffDepartment of Urology, Medway NHS Foundation Trust, Windmill Road, Gillingham ME7 5NY, UK.
Cyrus ChargariDepartment of Medical Oncology, Gustave Roussy Institut, 94805 Villejuif, France.ORCID 0000-0003-0119-3695
Nicholas PavlidisMedical School, University of Ioannina, Stavros Niarchou Avenue, 45110 Ioannina, Greece.
Institut Gustave Roussy · FRMedway NHS Foundation Trust · GBKing's College London · GBNovartis (Switzerland) · CHSt Bartholomew's Hospital · GBSt Thomas' Hospital · GBUniversity of Ioannina · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DNA damage repair (DDR) defects are common in different cancer types, and these alterations can be exploited therapeutically. Epithelial ovarian cancer (EOC) is among the tumours with the highest percentage of hereditary cases.

Indexed as

DNA damage repairhomologous recombinationovarian cancerPARP inhibitorsprostate cancer

Identifiers

PMID36010882
PMCPMC9405840
OpenAlexW4291011829

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.