Evidence map›Paper›PMID 36011306›Full record

ArticleGenes2022

Patient-Derived iPSCs Reveal Evidence of Telomere Instability and DNA Repair Deficiency in Coats Plus Syndrome.

Noufissa Oudrhiri, Radhia M'kacher, Diana Chaker, Bruno Colicchio, Claire Borie, Eric Jeandidier, Alain Dieterlen, Frank Griscelli, Annelise Bennaceur-Griscelli, Ali G Turhan

Open access · goldAbstract read
In one paragraph

Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Extended lifespan and improved genome stability in HepaRG-derived cell lines through reprogramming by high-density stress.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Noufissa OudrhiriInserm UMR_S_1310, 94805 Villejuif, France.
Radhia M'kacherInserm UMR_S_1310, 94805 Villejuif, France.ORCID 0000-0003-0639-4760
Diana ChakerINGESTEM National iPSC Infrastructure, 94805 Villejuif, France.ORCID 0000-0003-2670-8341
Bruno ColicchioIRIMAS, Institut de Recherche en Informatique, Mathématiques, Automatique et Signal, Université de Haute-Alsace, 68070 Mulhouse, France.ORCID 0000-0002-1742-8631
Claire BorieInserm UMR_S_1310, 94805 Villejuif, France.
Eric JeandidierLaboratoire de Génétique, Groupe Hospitalier de la Région de Mulhouse Sud-Alsace, 68070 Mulhouse, France.ORCID 0000-0002-2757-0770
Alain DieterlenIRIMAS, Institut de Recherche en Informatique, Mathématiques, Automatique et Signal, Université de Haute-Alsace, 68070 Mulhouse, France.
Frank GriscelliINGESTEM National iPSC Infrastructure, 94805 Villejuif, France.
Annelise Bennaceur-GriscelliInserm UMR_S_1310, 94805 Villejuif, France.
Ali G TurhanInserm UMR_S_1310, 94805 Villejuif, France.ORCID 0000-0002-4861-0137
Inserm · FRUniversité de Haute-Alsace · FRDélégation Paris 5 · FRGroupe Hospitalier de la Région de Mulhouse et Sud Alsace · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coats plus (CP) syndrome is an inherited autosomal recessive condition that results from mutations in the conserved telomere maintenance component 1 gene (

Indexed as

DNA Repair-Deficiency DisordersInduced Pluripotent Stem CellsTelomeraseAtaxiaBrain NeoplasmsCalcinosisCentral Nervous System CystsHumansLeukoencephalopathiesMuscle SpasticityRetinal DiseasesSeizuresTelomereTelomere HomeostasisTelomerasealternative lengthening of telomere (ALT)chromosomal instabilityCoats plus syndromeCTC1telomerasetelomere

Identifiers

PMID36011306
PMCPMC9407572
OpenAlexW4290596787

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.