Evidence map›Paper›PMID 36012216›Full record

ReviewInternational journal of molecular sciences2022

Genomic Analyses of Non-Coding RNAs Overlapping Transposable Elements and Its Implication to Human Diseases.

Eun Gyung Park, Hongseok Ha, Du Hyeong Lee, Woo Ryung Kim, Yun Ju Lee, Woo Hyeon Bae, Heui-Soo Kim

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 46 citations in OpenAlex.

  1. Review
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  7. Molecular drivers of RNA phase separation.Proceedings of the National Academy of Sciences of the United States of America · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Eun Gyung ParkDepartment of Integrated Biological Sciences, Pusan National University, Busan 46241, Korea.ORCID 0000-0002-9575-7043
Hongseok HaDivision of Life Sciences, Korea University, Seoul 02841, Korea.
Du Hyeong LeeDepartment of Integrated Biological Sciences, Pusan National University, Busan 46241, Korea.
Woo Ryung KimDepartment of Integrated Biological Sciences, Pusan National University, Busan 46241, Korea.
Yun Ju LeeDepartment of Integrated Biological Sciences, Pusan National University, Busan 46241, Korea.
Woo Hyeon BaeDepartment of Integrated Biological Sciences, Pusan National University, Busan 46241, Korea.
Heui-Soo KimInstitute of Systems Biology, Pusan National University, Busan 46241, Korea.
Pusan National University · KRKorea University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is estimated that up to 80% of the human genome is transcribed into RNA molecules but less than 2% of the genome encodes the proteins, and the rest of the RNA transcripts that are not translated into protein are called non-coding RNAs (ncRNAs). Many studies have revealed that ncRNAs have biochemical activities as epigenetic regulators at the post-transcriptional level. Growing evidence has demonstrated that transposable elements (TEs) contribute to a large percentage of ncRNAs' transcription. The TEs inserted into certain parts of the genome can act as alternative promoters, enhancers, and insulators, and the accumulation of TEs increases genetic diversity in the human genome. The TEs can also generate microRNAs, so-called miRNA-derived from transposable elements (MDTEs), and are also implicated in disease progression, such as infectious diseases and cancer. Here, we analyzed the origin of ncRNAs and reviewed the published literature on MDTEs related to disease progression.

Indexed as

DNA Transposable ElementsMicroRNAsDisease ProgressionGenomicsHumansRNA, UntranslatedDNA Transposable ElementsMicroRNAsRNA, Untranslateddiseaselong non-coding RNAMDTEnon-coding RNAtransposable element

Identifiers

PMID36012216
PMCPMC9409130
OpenAlexW4291000127

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.