Evidence map›Paper›PMID 36012225›Full record

ArticleInternational journal of molecular sciences2022

Identification of Pri-miRNA Stem-Loop Interacting Proteins in Plants Using a Modified Version of the Csy4 CRISPR Endonuclease.

Janina Lüders, Andreas R Winkel, Marlene Reichel, Valentin W Bitterer, Marion Scheibe, Christiane Widmann, Falk Butter, Tino Köster

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Janina LüdersDepartment of RNA Biology and Molecular Physiology, Faculty of Biology, Bielefeld University, D-33615 Bielefeld, Germany.
Andreas R WinkelDepartment of RNA Biology and Molecular Physiology, Faculty of Biology, Bielefeld University, D-33615 Bielefeld, Germany.
Marlene ReichelDepartment of RNA Biology and Molecular Physiology, Faculty of Biology, Bielefeld University, D-33615 Bielefeld, Germany.
Valentin W BittererDepartment of RNA Biology and Molecular Physiology, Faculty of Biology, Bielefeld University, D-33615 Bielefeld, Germany.ORCID 0000-0003-1549-2856
Marion ScheibeQuantitative Proteomics, Institute of Molecular Biology (IMB), D-55128 Mainz, Germany.
Christiane WidmannStructural Biochemistry, Department of Chemistry, Bielefeld University, D-33615 Bielefeld, Germany.
Falk ButterQuantitative Proteomics, Institute of Molecular Biology (IMB), D-55128 Mainz, Germany.
Tino KösterDepartment of RNA Biology and Molecular Physiology, Faculty of Biology, Bielefeld University, D-33615 Bielefeld, Germany.ORCID 0000-0003-3984-9813
Bielefeld University · DEInstitute of Molecular Biology · DE

Funding

Deutsche Forschungsgemeinschaft KO 5364/1-1
6 · The paper itself

Abstract

Regulation at the RNA level by RNA-binding proteins (RBPs) and microRNAs (miRNAs) is key to coordinating eukaryotic gene expression. In plants, the importance of miRNAs is highlighted by severe developmental defects in mutants impaired in miRNA biogenesis. MiRNAs are processed from long primary-microRNAs (pri-miRNAs) with internal stem-loop structures by endonucleolytic cleavage. The highly structured stem-loops constitute the basis for the extensive regulation of miRNA biogenesis through interaction with RBPs. However,

Indexed as

ArabidopsisArabidopsis ProteinsMicroRNAsClustered Regularly Interspaced Short Palindromic RepeatsEndonucleasesGene Expression Regulation, PlantRibonuclease IIIRNA-Binding ProteinsRNA Processing, Post-TranscriptionalArabidopsis ProteinsEndonucleasesMicroRNAsRibonuclease IIIRNA-Binding ProteinsArabidopsisCsy4* CRISPR endonucleaseplantpri-miRNA stem-loopRNA-binding proteinRNA-protein interactionRNA pulldown

Identifiers

PMID36012225
PMCPMC9409100
OpenAlexW4291011182

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.