Evidence map›Paper›PMID 36012314›Full record

ArticleInternational journal of molecular sciences2022

Aberrant Retinal Pigment Epithelial Cells Derived from Induced Pluripotent Stem Cells of a Retinitis Pigmentosa Patient with the PRPF6 Mutation.

Yuqin Liang, Feng Tan, Xihao Sun, Zekai Cui, Jianing Gu, Shengru Mao, Hon Fai Chan, Shibo Tang, Jiansu Chen

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Neurodegenerative spliceosomopathies.Frontiers in cell and developmental biology · 2026
    Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Addressing the tissue specificity of U5 snRNP spliceosomopathies.Frontiers in cell and developmental biology · 2025
    Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Yuqin LiangAier School of Ophthalmology, Central South University, Changsha 410015, China.ORCID 0000-0002-2448-4746
Feng TanAier School of Ophthalmology, Central South University, Changsha 410015, China.
Xihao SunAier School of Ophthalmology, Central South University, Changsha 410015, China.
Zekai CuiAier School of Ophthalmology, Central South University, Changsha 410015, China.
Jianing GuAier Eye Institute, Changsha 410015, China.
Shengru MaoAier Eye Institute, Changsha 410015, China.
Hon Fai ChanInstitute for Tissue Engineering and Regenerative Medicine, The Chinese University of Hong Kong, Hong Kong 999077, China.ORCID 0000-0003-0573-1251
Shibo TangAier School of Ophthalmology, Central South University, Changsha 410015, China.
Jiansu ChenAier School of Ophthalmology, Central South University, Changsha 410015, China.ORCID 0000-0001-6703-9573
Central South University · CNChinese University of Hong Kong · HK

Funding

National Natural Science Foundation of China 32061160469Science and Technology Project of Guangdong Province 2021A0505110005Science Research Grant of Aier Eye Institute 02-202105
6 · The paper itself

Abstract

Pre-mRNA processing factors (PRPFs) are vital components of the spliceosome and are involved in the physiological process necessary for pre-mRNA splicing to mature mRNA. As an important member,

Indexed as

Induced Pluripotent Stem CellsRetinitis PigmentosaCell DifferentiationEpithelial CellsHumansLeukocytes, MononuclearMutationRetinal Pigment EpitheliumRetinal PigmentsRNA PrecursorsRNA Splicing FactorsTranscription FactorsPRPF6 protein, humanRetinal PigmentsRNA PrecursorsRNA Splicing FactorsTranscription Factorsdisease modelPRPF6retinal pigment epitheliumretinitis pigmentosa

Identifiers

PMID36012314
PMCPMC9409096
OpenAlexW4291889309

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.