ArticleInternational journal of molecular sciences2022
Sex as Biological Variable in Cardiac Mitochondrial Bioenergetic Responses to Acute Stress.
Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Cardioprotection Through Mitochondrial Modulation: A Systematic Review of Pharmacological Interventions in Animal Models of I/R Injury.Cardiovascular drugs and therapy · 2026Pooled it
- Sex differences in human umbilical vein endothelial cells following ox-LDL injury.Biology of sex differences · 2026Article
- Direct exposure to vinclozolin induces sex-dependent mitochondrial dysfunction in mouse liver.Current research in toxicology · 2026Article
- Article
- Isolated mouse adult cardiomyocytes display minimal mitochondrial ATP demand and maximal reliance on glycolysis.Journal of molecular and cellular cardiology · 2025Article
- Sex-Specific Differences in LPS-Induced Rapid Myocardial Dysfunction.International journal of molecular sciences · 2025Article
- An investigation into the sex dependence of post-reperfusion cardiac mitochondrial function and redox balance in chronically stressed rats.Physiological reports · 2025Article
- AMPK regulates Bcl2-L-13-mediated mitophagy induction for cardioprotection.Cell reports · 2024Article
- An update on the role of sex hormones in the function of the cardiorenal mitochondria.Biochemical Society transactions · 2024Review
- Contribution of Sex Differences to the Development of Cardiovascular Disease in Metabolic-Associated Steatotic Liver Disease (MASLD).International journal of translational medicine (Basel, Switzerland) · 2024Article
- Sex in cardiovascular disease: Why this biological variable should be considered in in vitro models.Science advances · 2024Review
- Importance of Per2 in cardiac mitochondrial protection during stress.Scientific reports · 2024Article
- Male and Female Mitochondria Respond Differently after Exercising in Acute Hypoxia.Biomedicines · 2023Article
- Exercise intensity and sex alter neurometabolic, transcriptional, and functional recovery following traumatic brain injury.Experimental neurology · 2023Article
- Interactions between Gender and Sepsis-Implications for the Future.Microorganisms · 2023Review
- The sex-dependent response to psychosocial stress and ischaemic heart disease.Frontiers in cardiovascular medicine · 2023Review
- Sex Differences in X-ray-Induced Endothelial Damage: Effect of Taurine and N-Acetylcysteine.Antioxidants (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Cardiac dysfunction/damage following trauma, shock, sepsis, and ischemia impacts clinical outcomes. Acute inflammation and oxidative stress triggered by these injuries impair mitochondria, which are critical to maintaining cardiac function. Despite sex dimorphisms in consequences of these injuries, it is unclear whether mitochondrial bioenergetic responses to inflammation/oxidative stress are sex-dependent. We hypothesized that sex disparity in mitochondrial bioenergetics following TNFα or H
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.