Evidence map›Paper›PMID 36012714›Full record

ReviewInternational journal of molecular sciences2022

The Role and Regulatory Mechanism of Brown Adipose Tissue Activation in Diet-Induced Thermogenesis in Health and Diseases.

Pei-Chi Chan, Po-Shiuan Hsieh

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Pei-Chi ChanDepartment of Physiology & Biophysics, National Defense Medical Center (NDMC), 161, Section 6 Min-Chuan East Road, Taipei 114, Taiwan.
Po-Shiuan HsiehDepartment of Physiology & Biophysics, National Defense Medical Center (NDMC), 161, Section 6 Min-Chuan East Road, Taipei 114, Taiwan.
National Defense Medical Center · TW

Funding

Chi-Mei Medical Center CMNDMC 108-03Ministry of Science and Technology of the R.O.C. MOST 110-2320-B-016-003Ministry of Science and Technology of the R.O.C. MOST 111-2320-B-016-003 -MY3Ministry of Science and Technology of the R.O.C. MOST 111-2320-B-016-016
6 · The paper itself

Abstract

Brown adipose tissue (BAT) has been considered a vital organ in response to non-shivering adaptive thermogenesis, which could be activated during cold exposure through the sympathetic nervous system (SNS) or under postprandial conditions contributing to diet-induced thermogenesis (DIT). Humans prefer to live within their thermal comfort or neutral zone with minimal energy expenditure created by wearing clothing, making shelters, or using an air conditioner to regulate their ambient temperature; thereby, DIT would become an important mechanism to counter-regulate energy intake and lipid accumulation. In addition, there has been a long interest in the intriguing possibility that a defect in DIT predisposes one to obesity and other metabolic diseases. Due to the recent advances in methodology to evaluate the functional activity of BAT and DIT, this updated review will focus on the role and regulatory mechanism of BAT biology in DIT in health and diseases and whether these mechanisms are applicable to humans.

Indexed as

Adipose Tissue, BrownThermogenesisCold TemperatureEnergy IntakeEnergy MetabolismHumansObesitybrown adipose tissuediet-induced thermogenesis

Identifiers

PMID36012714
PMCPMC9408971
OpenAlexW4293680850

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.