Evidence map›Paper›PMID 36013672›Full record

ArticleMaterials (Basel, Switzerland)2022

Green Facile Synthesis of Silver-Doped Zinc Oxide Nanoparticles and Evaluation of Their Effect on Drug Release.

Nadia Mahmoudi Khatir, Farzaneh Sabbagh

Open access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Nadia Mahmoudi KhatirDepartment of Biotechnology, Faculty of Biological Sciences, Alzahra University, Tehran 1993891176, Iran.ORCID 0000-0002-8176-1535
Farzaneh SabbaghDepartment of Chemical Engineering, Chungbuk National University, Cheongju 28644, Korea.
Alzahra University · IRChungbuk National University · KR

Funding

Iran National Science Foundation 94027600
6 · The paper itself

Abstract

Silver doped zinc oxide nanoparticles (ZANPs) were synthesized by the gelatin mediated and polymerized sol-gel method, and a calcination temperature of 700 °C was applied for 2 h. X-ray diffraction (XRD), FESEM, TGA, DSC, and EDS were performed to study the structure of the prepared nano-powders. Both cubic silver and hexagonal ZnO diffraction peaks were detected in the XRD patterns. The XRD results, analyzed by the size strain plot (SSP) and Scherrer methods, showed that the crystalline sizes of these nanoparticles increased as the Ag concentration increased. The results were observed via transition electron microscopy (TEM), where the particle size of the prepared samples was increased in the presence of silver. Catechin was chosen as a drug model and was loaded into the hydrogels for release studies. The drug content percentage of catechin in the hydrogels showed a high loading of the drug, and the highest rate was 98.59 ± 2.11%, which was attributed to the Zn0.97Ag0.03O hydrogels. The swelling of the samples and in vitro release studies were performed. The results showed that Zn0.91Ag0.09O showed the highest swelling ratio (68 ± 3.40%) and, consequently, the highest release (84 ± 2.18%) within 300 min. The higher amount of silver ions in the hydrogel structure causes it to enhance the osmotic pressure of the inner structure and increases the relaxation of the structure chain.

Indexed as

Ag-ZnO nanoparticlesbiopolymerdrug releasegreen synthesisκ-Carrageenan

Identifiers

PMID36013672
PMCPMC9414952
OpenAlexW4291001084

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.