Evidence map›Paper›PMID 36014889›Full record

ReviewNutrients2022

Vitamin-Microbiota Crosstalk in Intestinal Inflammation and Carcinogenesis.

Zihan Zhai, Wenxiao Dong, Yue Sun, Yu Gu, Jiahui Ma, Bangmao Wang, Hailong Cao

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Zihan ZhaiDepartment of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Tianjin 300052, China.
Wenxiao DongDepartment of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Tianjin 300052, China.
Yue SunDepartment of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Tianjin 300052, China.
Yu GuDepartment of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Tianjin 300052, China.
Jiahui MaDepartment of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Tianjin 300052, China.
Bangmao WangDepartment of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Tianjin 300052, China.
Hailong CaoDepartment of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Tianjin 300052, China.ORCID 0000-0002-0147-7826
Tianjin Medical University General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory bowel disease (IBD) and colitis-associated colorectal cancer (CAC) are common diseases of the digestive system. Vitamin deficiencies and gut microbiota dysbiosis have a close relationship with the risk, development, and progression of IBD and CAC. There is a strong link between vitamins and the gut microbiome. Vitamins are extremely crucial for maintaining a healthy gut microbiota, promoting growth and development, metabolism, and innate immunity. Gut microbiota can not only influence the transport process of vitamins, but also produce vitamins to compensate for insufficient food intake. Emerging evidence suggests that oral vitamin supplementation can reduce inflammation levels and improve disease prognosis. In addition, improving the diet structure and consuming foods rich in vitamins not only help to improve the vitamin deficiency, but also help to reduce the risk of IBD. Fecal microbiota transplantation (FMT) and the application of vitamin-producing probiotics can better assist in the treatment of intestinal diseases. In this review, we discuss the interaction and therapeutic roles of vitamins and gut microbiota in IBD and CAC. We also summarize the methods of treating IBD and CAC by modulating vitamins. This may highlight strategies to target gut-microbiota-dependent alterations in vitamin metabolism in the context of IBD and CAC therapy.

Indexed as

Inflammatory Bowel DiseasesMicrobiotaCarcinogenesisDysbiosisHumansInflammationVitaminsVitaminsCACIBDmicrobiometherapyvitamins

Identifiers

PMID36014889
PMCPMC9414212
OpenAlexW4292260372

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.