Evidence map›Paper›PMID 36015121›Full record

ReviewPharmaceuticals (Basel, Switzerland)2022

Health Benefits and Pharmacological Aspects of Chrysoeriol.

Sara Aboulaghras, Nargis Sahib, Saad Bakrim, Taoufiq Benali, Saoulajan Charfi, Fatima-Ezzahrae Guaouguaou, Nasreddine El Omari, Monica Gallo, Domenico Montesano, Gokhan Zengin and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
12.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 71 citations in OpenAlex.

  1. Article
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  9. Bioactive Compounds Isolated from the Species of theMolecules (Basel, Switzerland) · 2025
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  15. Herbicidal Activity and Metabolic Profiling ofJournal of agricultural and food chemistry · 2025
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  17. Research Progress on Anti-Inflammatory Mechanism ofInternational journal of molecular sciences · 2025
    Review
  18. Current issues in molecular biology · 2025
    Article
  19. Overview of theLife (Basel, Switzerland) · 2025
    Review
  20. Plants (Basel, Switzerland) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 3 countries.

Sara AboulaghrasPhysiology and Physiopathology Team, Faculty of Sciences, Genomic of Human Pathologies Research, Mohammed V University in Rabat, Rabat 10100, Morocco.
Nargis SahibLaboratoire d'Amélioration des Productions Agricoles, Biotechnologie et Environnement (LAPABE), Faculté des Sciences, Mohammed Premier University, Oujda 60000, Morocco.ORCID 0000-0002-9676-7585
Saad BakrimGeo-Bio-Environment Engineering and Innovation Laboratory, Molecular Engineering, Biotechnologies and Innovation Team, Polydisciplinary Faculty of Taroudant, Ibn Zohr University, Agadir 80000, Morocco.ORCID 0000-0002-4521-3515
Taoufiq BenaliEnvironment and Health Team, Polydisciplinary Faculty of Safi, Cadi Ayyad University, Marrakesh-Safi 46030, Morocco.ORCID 0000-0001-5732-2818
Saoulajan CharfiLaboratory of Biotechnology and Applied Microbiology, Department of Biology, Faculty of Sciences, Abdelmalek Essaadi University, Tetouan 93030, Morocco.ORCID 0000-0002-0758-7727
Fatima-Ezzahrae GuaouguaouLPCMIO, Materials Science Center (MSC), Ecole Normale Supérieure de Rabat, Mohammed V University in Rabat, Rabat 10100, Morocco.
Nasreddine El OmariLaboratory of Histology, Embryology, and Cytogenetic, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Rabat 10100, Morocco.ORCID 0000-0002-0308-1155
Monica GalloDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Via Pansini 5, 80131 Naples, Italy.ORCID 0000-0001-6281-426X
Domenico MontesanoDepartment of Pharmacy, University of Naples Federico II, Via D. Montesano 49, 80131 Naples, Italy.ORCID 0000-0002-8857-2091
Gokhan ZenginDepartment of Biology, Science Faculty, Selcuk University, Konya 42250, Turkey.ORCID 0000-0001-6548-7823
Khalid TaghzoutiPhysiology and Physiopathology Team, Faculty of Sciences, Genomic of Human Pathologies Research, Mohammed V University in Rabat, Rabat 10100, Morocco.
Abdelhakim BouyahyaLaboratory of Human Pathologies Biology, Department of Biology, Faculty of Sciences, Mohammed V University in Rabat, Rabat 10100, Morocco.ORCID 0000-0001-9317-1631
Mohammed V University · MAUniversity of Naples Federico II · ITAbdelmalek Essaâdi University · MACadi Ayyad University · MASelçuk University · TRUniversité Hassan II Mohammedia · MAUniversité Ibn Zohr · MA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A flavone, chrysoeriol is synthetized in several plant species. It comes from several natural sources, especially medicinal plants. The identification and isolation of this compound has been carried out and verified by several research teams using different spectral methods. It seems that the concentration of this molecule is variable and fluctuating depending on the source, the part extracted, the region, and the methods of extraction and characterization. The aim of this paper is to highlight the in vitro and in vivo pharmacological properties of chrysoeriol and to provide insight into its pharmacokinetics. Anticancer, anti-inflammatory, antibacterial, antifungal, anti-osteoporosis, anti-insecticide, and neuroprotective actions have been shown in a number of studies on this chemical. Different mechanisms in theses pharmacological effects include subcellular, cellular, and molecular targets. In vivo pharmacokinetic analysis has proved the good stability of this molecule, showing its promising potential to prevent or treat diseases including cancer, diabetes, inflammation, osteoporosis, Parkinson's disease, and cardiovascular diseases.

Indexed as

biological activitieschrysoeriolpharmacodynamicpharmacokinetic

Identifiers

PMID36015121
PMCPMC9415049
OpenAlexW4290759893

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.