Evidence map›Paper›PMID 36015290›Full record

ArticlePharmaceutics2022

Ruthenium(II) Polypyridyl Complexes for Antimicrobial Photodynamic Therapy: Prospects for Application in Cystic Fibrosis Lung Airways.

Raphaëlle Youf, Adeel Nasir, Mareike Müller, Franck Thétiot, Tanguy Haute, Rosy Ghanem, Ulrich Jonas, Holger Schönherr, Gilles Lemercier, Tristan Montier and 1 more

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Photodynamic Eradication ofPharmaceutics · 2023
    Article
  6. Recent Advances in Metal Complexes for Antimicrobial Photodynamic Therapy.Chembiochem : a European journal of chemical biology · 2023
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Raphaëlle YoufINSERM, Univ Brest, EFS, UMR 1078, GGB-GTCA, 29200 Brest, France.
Adeel NasirINSERM, Univ Brest, EFS, UMR 1078, GGB-GTCA, 29200 Brest, France.
Mareike MüllerPhysical Chemistry I & Research Center of Micro- and Nanochemistry and (Bio)Technology (Cμ), Department of Chemistry and Biology, University of Siegen, 57076 Siegen, Germany.
Franck ThétiotUnité Mixte de Recherche (UMR), Centre National de la Recherche Scientifique (CNRS) 6521, Université de Brest (UBO), CS 93837, 29238 Brest, France.
Tanguy HauteINSERM, Univ Brest, EFS, UMR 1078, GGB-GTCA, 29200 Brest, France.ORCID 0000-0002-7256-1785
Rosy GhanemINSERM, Univ Brest, EFS, UMR 1078, GGB-GTCA, 29200 Brest, France.ORCID 0000-0002-3336-6629
Ulrich JonasMacromolecular Chemistry, Department of Chemistry and Biology, University of Siegen, 57076 Siegen, Germany.ORCID 0000-0002-2161-4541
Holger SchönherrPhysical Chemistry I & Research Center of Micro- and Nanochemistry and (Bio)Technology (Cμ), Department of Chemistry and Biology, University of Siegen, 57076 Siegen, Germany.ORCID 0000-0002-5836-5569
Gilles LemercierCoordination Chemistry Team, Unité Mixte de Recherche (UMR), Centre National de la Recherche Scientifique (CNRS) 7312, Institut de Chimie Moléculaire de Reims (ICMR), Université de Reims Champagne-Ardenne, BP 1039, CEDEX 2, 51687 Reims, France.ORCID 0000-0002-6889-7059
Tristan MontierINSERM, Univ Brest, EFS, UMR 1078, GGB-GTCA, 29200 Brest, France.ORCID 0000-0003-0452-6395
Tony Le GallINSERM, Univ Brest, EFS, UMR 1078, GGB-GTCA, 29200 Brest, France.ORCID 0000-0001-5922-5683
Inserm · FRUniversity of Siegen · DECentre National de la Recherche Scientifique · FR

Funding

Agence Nationale de la Recherche ANR-20-AMRB-0009, RPV21103NNA
6 · The paper itself

Abstract

Antimicrobial photodynamic therapy (aPDT) depends on a variety of parameters notably related to the photosensitizers used, the pathogens to target and the environment to operate. In a previous study using a series of Ruthenium(II) polypyridyl ([Ru(II)]) complexes, we reported the importance of the chemical structure on both their photo-physical/physico-chemical properties and their efficacy for aPDT. By employing standard in vitro conditions, effective [Ru(II)]-mediated aPDT was demonstrated against planktonic cultures of

Indexed as

antimicrobial photodynamic therapyantimicrobial resistancebenchmark analysisbiofilmcystic fibrosismicro-environmentruthenium complexes

Identifiers

PMID36015290
PMCPMC9412327
OpenAlexW4293511139

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.