Evidence map›Paper›PMID 36017197›Full record

ArticlePathology oncology research : POR2022

Association Between Vitamin D Binding Protein Gene Polymorphism (rs7041), Vitamin D Receptor, and 25-Hydroxyvitamin D Serum Levels With Prostate Cancer in Kurdish Population in West of Iran.

Mohammad Amiri, Daniel Elieh Ali Komi, Asad Vaisi-Raygani, Amir Kiani, Mahmoudreza Moradi, Mahdieh Aliyari, Zohreh Rahimi, Ehsan Mohammadi-Noori, Homayoon Bashiri

Open access · goldAbstract read
In one paragraph

Article in Pathology oncology research : POR, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. The double disparity: Vitamin D deficiency and lethal prostate cancer in black men.The Journal of steroid biochemistry and molecular biology · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Mohammad AmiriStudent Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Daniel Elieh Ali KomiRegenerative Medicine Research Center (RMRC), Kermanshah University of Medical Sciences, Kermanshah, Iran.
Asad Vaisi-RayganiFertility and Infertility Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Amir KianiRegenerative Medicine Research Center (RMRC), Kermanshah University of Medical Sciences, Kermanshah, Iran.
Mahmoudreza MoradiRegenerative Medicine Research Center (RMRC), Kermanshah University of Medical Sciences, Kermanshah, Iran.
Mahdieh AliyariStudent Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Zohreh RahimiMedical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Ehsan Mohammadi-NooriPharmaceutical Sciences Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Homayoon BashiriDepartment of Internal Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Kermanshah University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer (PCa) pathology has been linked to vitamin D, vitamin D receptors (VDRs), and vitamin D binding proteins (VDBPs). We sought to investigate the association between VDR rs2228570 and rs1544410 as well as VDBP rs7041 polymorphisms and serum 25-hydroxyvitamin D (25(OH)-vitamin D) levels in PCa patients. Blood samples were collected from 111 PCa patients and 150 age-matched healthy volunteers. The VDR rs2228570 T/C, rs1544410 G/A, and VDBP rs7041 T/G genotypes were determined using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). 25(OH)-vitamin D and PSA (Total and Free) serum levels were measured. The frequencies of VDBP genotypes T/G vs. T/T (56.5% vs. 44.5%,

Indexed as

Prostatic NeoplasmsVitamin D-Binding ProteinCase-Control StudiesGenetic Predisposition to DiseaseGenotypeHumansIranMalePolymorphism, Single NucleotideProstate-Specific AntigenReceptors, CalcitriolVitamin D25-hydroxyvitamin DGC protein, humanProstate-Specific AntigenReceptors, CalcitriolVDR protein, humanVitamin DVitamin D-Binding Protein25(OH)-vitamin Dpolymorphismprostate cancervitamin D binding proteinvitamin D receptor

Identifiers

PMID36017197
PMCPMC9395586
OpenAlexW4290739317

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.