Evidence map›Paper›PMID 36028219›Full record

ReviewWIREs mechanisms of disease2023

Models of the cardiac L-type calcium current: A quantitative review.

Aditi Agrawal, Ken Wang, Liudmila Polonchuk, Jonathan Cooper, Maurice Hendrix, David J Gavaghan, Gary R Mirams, Michael Clerx

Abstract readReview
In one paragraph

Review in WIREs mechanisms of disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. CaJournal of molecular and cellular cardiology · 2023
    Article
  5. Review
  6. Ion channel model reduction using manifold boundaries.Journal of the Royal Society, Interface · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Aditi AgrawalComputational Biology & Health Informatics, Department of Computer Science, University of Oxford, Oxford, UK.ORCID 0000-0001-8651-9062
Ken WangPharma Research and Early Development, Innovation Center Basel, F. Hoffmann-La Roche Ltd., Basel, Switzerland.ORCID 0000-0003-3497-5458
Liudmila PolonchukPharma Research and Early Development, Innovation Center Basel, F. Hoffmann-La Roche Ltd., Basel, Switzerland.ORCID 0000-0002-6947-2845
Jonathan CooperCentre for Advanced Research Computing, University College London, London, UK.ORCID 0000-0001-6009-3542
Maurice HendrixCentre for Mathematical Medicine & Biology, School of Mathematical Sciences, University of Nottingham, Nottingham, UK.ORCID 0000-0002-6621-7996
David J GavaghanComputational Biology & Health Informatics, Department of Computer Science, University of Oxford, Oxford, UK.ORCID 0000-0001-8311-3200
Gary R MiramsCentre for Mathematical Medicine & Biology, School of Mathematical Sciences, University of Nottingham, Nottingham, UK.ORCID 0000-0002-4569-4312
Michael ClerxCentre for Mathematical Medicine & Biology, School of Mathematical Sciences, University of Nottingham, Nottingham, UK.ORCID 0000-0003-4062-3061

Funding

Biotechnology and Biological Sciences Research Council BB/P010008/1Wellcome Trust 212203/Z/18/Z
6 · The paper itself

Abstract

The L-type calcium current (

Indexed as

Cardiovascular DiseasesMyocytes, CardiacAnimalsArrhythmias, CardiacCalcium, DietaryMammalsMutationCalcium, Dietarycalcium channelcellular electrophysiologycomputational modelL-type calcium current

Identifiers

PMID36028219
PMCPMC10078428

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.