ReviewEndocrine2022
Type 2 diabetes in children and adolescents: distinct characteristics and evidence-based management.
Review in Endocrine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 13 citations in OpenAlex.
- Central adiposity outperforms disordered eating behavior in predicting type 2 diabetes risk in young adults: an explainable machine learning approach.Frontiers in public health · 2026Article
- Global trends and hotspots of type 2 diabetes in children and adolescents: A bibliometric study and visualization analysis.World journal of diabetes · 2025Article
- Type 2 diabetes in children and adolescents: Exploring the disease heterogeneity and research gaps to optimum management.World journal of clinical pediatrics · 2024Review
- Prediabetes in children and adolescents: An updated review.World journal of clinical pediatrics · 2023Review
- Unmet Needs in the Treatment of Childhood Type 2 Diabetes: A Narrative Review.Advances in therapy · 2023Review
- Beta Cell Dysfunction in Youth- and Adult-Onset Type 2 Diabetes: An Extensive Narrative Review with a Special Focus on the Role of Nutrients.Nutrients · 2023Review
- Antidiabetic Activities of 80% Methanol Extract and Solvent Fractions ofJournal of experimental pharmacology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeSince the dramatic rise of obesity prevalence in childhood and adolescence has contributed to increased rates of type 2 diabetes (T2D) in youth, we sought to explore current evidence-based management options for pediatric T2D patients.
methodsA comprehensive literature search was performed for studies of T2D in childhood and adolescence until September 2021.
resultsSpecial pathophysiological and diagnostic characteristics of T2D in this age are presented, while the main focus of the article is on management. Lifestyle interventions with healthy diet and exercise are of great importance for the treatment of T2D in children and adolescents. Metformin and insulin remain the traditional therapeutical means, while liraglutide recently gained indication for children older than 10 years both in USA and Europe. Data on the use, efficacy, safety and therapeutic considerations of other pharmacological treatments in children and adolescents with T2D are critically discussed.
conclusionAlthough many new and promising therapeutic strategies have been introduced during recent years for the management of T2D in adults, available therapeutic options for the management of pediatric T2D remain limited.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.