Evidence mapPaperPMID 36030415Full record

Trial reportJournal of managed care & specialty pharmacy2023

Matching-adjusted indirect comparison of phase 3 clinical trial outcomes of OC-01 (varenicline solution) nasal spray and lifitegrast 5% ophthalmic solution for the treatment of dry eye disease.

Darrell E White, Laura H Hendrix, Lucille Sun, Iris Tam, Marian Macsai, Andrea A Gibson

Open access · greenAbstract readClinical Trial, Phase II
In one paragraph

Trial report in Journal of managed care & specialty pharmacy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Darrell E WhiteSky Vison Center, Westlake, OH.
Laura H HendrixOyster Point Pharma, Inc., Princeton, NJ.
Lucille SunCOEUS Consulting Group, Philadelphia, PA.
Iris TamCOEUS Consulting Group, Philadelphia, PA.
Marian MacsaiOyster Point Pharma, Inc., Princeton, NJ.
Andrea A GibsonOyster Point Pharma, Inc., Princeton, NJ.
PA Consulting Group · GBWestlake Health Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Dry Eye SyndromesNasal SpraysData CollectionHumansOphthalmic SolutionsPhenylalanineSulfonesTreatment OutcomeVareniclinelifitegrastNasal SpraysOphthalmic SolutionsPhenylalanineSulfonesVarenicline

Identifiers

PMID36030415
PMCPMC10394217
OpenAlexW4299394916

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.