Evidence map›Paper›PMID 36034286›Full record

ArticleFrontiers in neurology2022

Progressive volume reduction and long-term aneurysmal collapse following flow diversion treatment of giant and symptomatic cerebral aneurysms.

Kristina Sirakova, Marin Penkov, Svetozar Matanov, Krasimir Minkin, Kristian Ninov, Asen Hadzhiyanev, Vasil Karakostov, Irena Ivanova, Stanimir Sirakov

Abstract read
In one paragraph

Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Obstructive hydrocephalus due to high-volume liquid embolic agent embolization for management of pediatric arteriovenous malformations: illustrative case.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025
    Article
  5. Article
  6. Article
  7. Letter to the Editor Response.Journal of neurosurgery. Case lessons · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kristina SirakovaRadiology Department, Alexandrovska Hospital, Sofia, Bulgaria.
Marin PenkovRadiology Department, University Hospital St Ivan Rilski, Sofia, Bulgaria.
Svetozar MatanovRadiology Department, University Hospital St Ivan Rilski, Sofia, Bulgaria.
Krasimir MinkinNeurosurgery Department, University Hospital St Ivan Rilski, Sofia, Bulgaria.
Kristian NinovNeurosurgery Department, University Hospital St Ivan Rilski, Sofia, Bulgaria.
Asen HadzhiyanevNeurosurgery Department, University Hospital St Ivan Rilski, Sofia, Bulgaria.
Vasil KarakostovNeurosurgery Department, University Hospital St Ivan Rilski, Sofia, Bulgaria.
Irena IvanovaClinical Laboratory Department, University Hospital St Ivan Rilski, Sofia, Bulgaria.
Stanimir SirakovRadiology Department, University Hospital St Ivan Rilski, Sofia, Bulgaria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The primary goal of conventional endovascular and microvascular approaches is the clinical and radiological resolution of the symptomatic aneurysm-induced mass effect. This study assessed the volume changes and mass effect reduction due to sac shrinkage after treatment with flow diverter stents (FD) for unruptured cerebral aneurysms. Methods: We analyzed retrospectively 36 symptomatic aneurysms that were larger or equal to 25 mm in diameter in patients treated at our center from January 2016 to April 2022. Radiological and clinical outcomes were analyzed, including aneurysmal volume changes and resolution of aneurysm-related symptoms. Results: At 6 months, 25 aneurysms decreased in size, 2 remained unchanged, and 9 aneurysms demonstrated a post-treatment dimensional increase. At 12 months, 30 aneurysms showed a progressive radiological volume reduction. Either no change or negligible shrinkage was observed in the remaining six aneurysms. At 24 months, 32 aneurysms showed aneurysmal shrinkage by a mean 47% volume loss with respect to baseline. At the last follow-up, all 13 patients who had presented with third cranial nerve palsy showed improvements. Complete reversal of the pretreatment edematous changes was confirmed in all cases. The overall post-treatment complication rate was 8.3%, as 3 patients experienced non-fatal delayed rupture of their aneurysm. There was no mortality in this study. Conclusion: Flow diversion could effectively induce progressive aneurysmal shrinkage and resolution of the mass effect associated with giant symptomatic cerebral aneurysms.

Indexed as

aneurysmembolizationflow diversiongiantshrinkage

Identifiers

PMID36034286
PMCPMC9403733

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.