SynthesisFrontiers in cardiovascular medicine2022
Associations between sleep duration and cardiovascular diseases: A meta-review and meta-analysis of observational and Mendelian randomization studies.
Synthesis in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Inadequate sleep increases stroke risk: evidence from a comprehensive meta-analysis of incidence and mortality.GeroScience · 2025Pooled it
- Prevalence and Determinants of Poor Sleep Quality Among Patients with Established Coronary Heart Disease in Kazakhstan: A Multi-Center Cross-Sectional Study.Medical sciences (Basel, Switzerland) · 2026Article
- Association of obstructive sleep apnoea with exercise capacity and mortality in a population-based study: results of SHIP-TREND.ERJ open research · 2026Article
- Association of Sleep Duration Ratio with a Reduced Risk of Heart Failure: Analysis of the 2017-2023 National Health and Nutrition Examination Survey.Journal of clinical medicine · 2026Article
- Circadian disruption of brain temperature and heart rate in two periods after intracerebral hemorrhage surgery: a retrospective study.Scientific reports · 2026Article
- The interactive effect of long nighttime sleep and daytime napping on QTc prolongation in hypertensive adults.BMC cardiovascular disorders · 2026Article
- Joint associations of device-measured step count and sleep duration with incident major adverse cardiovascular events: prospective analysis of the UK Biobank.EClinicalMedicine · 2026Article
- Physical activity monitoring using wearable devices based on machine learning algorithms.Frontiers in sports and active living · 2026Article
- Modifiable lifestyle factors and sudden cardiac death: mechanisms, evidence, and prevention strategies.Frontiers in cardiovascular medicine · 2026Review
- Sleep duration and prevalence of coronary artery disease among adults in Chongqing, China.Frontiers in epidemiology · 2026Article
- Optimal sleep duration for cardiovascular prevention in Eastern Mediterranean populations: insights from a prospective cohort study.BMC cardiovascular disorders · 2025Article
- CVD Mortality Disparities with Risk Factor Associations Across U.S. Counties.Healthcare (Basel, Switzerland) · 2025Article
- Sleep and Stroke-An Overlooked Bidirectional Influence: Why Should Sleep and Vascular Neurologists Work Closer?Journal of clinical medicine · 2025Article
- Menopause-Related Changes in Sleep and the Associations with Cardiometabolic Health: A Narrative Review.Healthcare (Basel, Switzerland) · 2025Review
- Sleep Irregularity, Circadian Disruption, and Cardiometabolic Disease Risk.Circulation research · 2025Review
- Sleep Duration Irregularity and Risk for Incident Cardiovascular Disease in the UK Biobank.Journal of the American Heart Association · 2025Article
- Multidimensional sleep profiles via machine learning and risk of dementia and cardiovascular disease.Communications medicine · 2025Article
- Cardiovascular risk in newly diagnosed patients with type 2 diabetes mellitus: a nationwide, facility-based, cross-sectional study in Bangladesh.International journal of cardiology. Cardiovascular risk and prevention · 2025Article
- From Single Movement Behaviors to Complete 24-h Behaviors Profiles and Multiple Health Outcomes-A Cross-Sectional Study Using Accelerometry.Scandinavian journal of medicine & science in sports · 2025Article
- Associations of reallocating sedentary leisure-time to alternative discretionary movement behaviours with incident cardiometabolic diseases in 0.5 million Chinese adults.The Lancet regional health. Western Pacific · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The associations between sleep duration and cardiovascular diseases (CVDs) have been explored in many observational studies. However, the causality of sleep duration and many CVDs, such as coronary artery disease (CAD), heart failure (HF), and stroke, remains unclear. In this study, we conducted a systematic meta-review and meta-analysis of the results of observational and Mendelian randomization (MR) studies to examine how sleep duration impacts the risk of CVDs. We searched articles published in English and before 10 September 2021 in PubMed, Web of Science, and Embase. The articles were screened independently by two reviewers to minimize potential bias. We combined the meta-analyses of observational studies and 11 MR studies and summarized evidence of the effect of sleep duration on the risk of CAD, HF, stroke, and cardiovascular and all-cause mortality. Results showed that (a) evidence is accumulating that short sleep duration is a causal risk factor for CAD and HF; (b) abundant evidence from observational studies supports that long sleep duration is associated with the risk of CAD, stroke, and mortality, and long sleep duration has no causal associations with stroke and CAD in the MR studies; the causation of long sleep duration and other CVDs should be further studied; and (c) emerging evidence indicates that an increase in hours of sleep is associated with a decreased risk of CAD. Finally, we discussed the underlying pathophysiological mechanisms underlying short sleep duration and CVDs and suggested that increasing sleep duration benefits cardiovascular health.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.