ReviewVirulence2022
The spectrum of clinical biomarkers in severe malaria and new avenues for exploration.
Review in Virulence, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- Association of uric acid levels with severity of Plasmodium infections: a systematic review and meta-analysis.Scientific reports · 2023Pooled it
- Malaria in pregnancy in India: a 50-year bird's eye.Frontiers in public health · 2023Pooled it
- Noninvasive malaria detection beyond blood sampling.Sensors & diagnostics · 2026Review
- Diagnostic challenges in malaria detection: A comparative diagnostic performance of HRP2-based rapid diagnostic tests, microscopy, and PCR at Bichena primary hospital, Northwest Ethiopia.Parasite epidemiology and control · 2026Article
- Plasma haem oxygenase-1 and interleukin-6 as adjunct host biomarkers associated with malaria.Frontiers in immunology · 2026Article
- Transfusion-transmittedThe Lancet regional health. Southeast Asia · 2025Review
- The diagnostic significance of neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio in malaria: insights and implications - a narrative review.Annals of medicine and surgery (2012) · 2025Review
- Serum Proteomics of Experimental Malaria-Associated ARDS Reveals a Regulation of Acute-Phase Response Proteins.Journal of immunology research · 2025Article
- Article
- Revolution in malaria detection: unveiling current breakthroughs and tomorrow's possibilities in biomarker innovation.Annals of medicine and surgery (2012) · 2024Review
- Extracellular Proteomic Profiling from the Erythrocytes Infected with Plasmodium Falciparum 3D7 Holds Promise for the Detection of Biomarkers.The protein journal · 2024Article
- Article
- Genetic diversity of merozoite surface protein-5 (MSP-5) of Plasmodium vivax isolates from Malaria patients in Iran.BMC infectious diseases · 2023Article
- Confounding role of comorbidities and COVID-19 vaccination uptake in clinical utility of hematological biomarkers in Cameroonian patients infected with SARS-CoV-2.IJID regions · 2023Article
- Nationwide spatiotemporal drug resistance genetic profiling from over three decades in Indian Plasmodium falciparum and Plasmodium vivax isolates.Malaria journal · 2023Article
- High Plasma Levels of Neopterin Are Associated with Increased Mortality among Children with Severe Malaria in Benin.Diagnostics (Basel, Switzerland) · 2023Article
- Phytofabrication and characterization ofFrontiers in bioengineering and biotechnology · 2023Article
- Non-falciparum species and submicroscopic infections in three epidemiological malaria facets in Cameroon.BMC infectious diseases · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Globally, malaria is a public health concern, with severe malaria (SM) contributing a major share of the disease burden in malaria endemic countries. In this context, identification and validation of SM biomarkers are essential in clinical practice. Some biomarkers (C-reactive protein, angiopoietin 2, angiopoietin-2/1 ratio, platelet count, histidine-rich protein 2) have yielded interesting results in the prognosis of
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.