Evidence map›Paper›PMID 36038697›Full record

ArticleMolecular neurobiology2022

Bone Marrow Mesenchymal Stem Cell Exosome Attenuates Inflammasome-Related Pyroptosis via Delivering circ_003564 to Improve the Recovery of Spinal Cord Injury.

Yanyin Zhao, Yu Chen, Zhiwei Wang, Changli Xu, Suchi Qiao, Tianze Liu, Ke Qi, Dake Tong, Cheng Li

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 43 citations in OpenAlex.

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  16. The roles of circular RNAs in nerve injury and repair.Frontiers in molecular neuroscience · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Yanyin Zhao *Department of Neurology, Huashan Hospital, Fudan University, Shanghai, China.
Yu Chen *Department of Orthopedics, Huashan Hospital, Fudan University, Shanghai, China.
Zhiwei WangDepartment of Orthopedics, Changhai Hospital, Naval Medical University, No. 168 Changhai Road, Shanghai, 200433, China.
Changli XuDepartment of Orthopedics, Changhai Hospital, Naval Medical University, No. 168 Changhai Road, Shanghai, 200433, China.
Suchi QiaoDepartment of Orthopedics, Changzheng Hospital, Naval Medical University, Shanghai, China.
Tianze LiuDepartment of Orthopedics, Changhai Hospital, Naval Medical University, No. 168 Changhai Road, Shanghai, 200433, China.
Ke QiDepartment of Orthopedics, Changhai Hospital, Naval Medical University, No. 168 Changhai Road, Shanghai, 200433, China.
Dake TongShanghai Key Laboratory of Orthopedic Implants, Department of Orthopedic Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, No. 639 Zhizaoju Road, Shanghai, 200011, China. duyou39935747@163.com.
Cheng LiDepartment of Orthopedics, Changhai Hospital, Naval Medical University, No. 168 Changhai Road, Shanghai, 200433, China. drchengli@163.com.ORCID http://orcid.org/0000-0001-7988-3835
Second Military Medical University · CNFudan University · CNShanghai Jiao Tong University · CN

Funding

National Natural Science Foundation of China No. 81801209Shanghai Clinical Medical Center Grant Number 2017ZZ01023Shanghai Health and Family Planning Commission Science Foundation No.201740213Shanghai Municipal Key Clinical Specialty Grant Number shslczdzk00402Shanghai Municipal Key Clinical Specialty shslczdzk07001
6 · The paper itself

Abstract

Bone marrow mesenchymal stem cell (BMSC) is previously reported to present a certain effect on treating spinal cord injury (SCI), while the underlying mechanism is largely uncovered. Therefore, the current study aimed to investigate the involvement of exosome-delivered circRNA profile in the BMSC's effect on pyroptosis for SCI treatment. H

Indexed as

Mesenchymal Stem CellsMesenchymal Stem Cell TransplantationSpinal Cord InjuriesAniline CompoundsAnimalsBenzylidene CompoundsCaspase 1Hydrogen PeroxideInflammasomesInterleukin-18Nerve Growth FactorNLR Family, Pyrin Domain-Containing 3 ProteinPyroptosisRatsRNA, CircularSpinal CordAniline CompoundsBenzylidene CompoundsCaspase 1GW 4869Hydrogen PeroxideInflammasomesInterleukin-18Nerve Growth FactorNLR Family, Pyrin Domain-Containing 3 ProteinRNA, CircularBone marrow mesenchymal stem cellCircular RNAExosomePyroptosisSpinal cord injury

Identifiers

PMID36038697
OpenAlexW4293733569

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.