Evidence map›Paper›PMID 36039591›Full record

ArticleZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences2022

Progress in the effect of microRNA-21 on diseases via autophagy.

Zhengpeng Zeng, Jinwen Cai, Yumei Liao, Shenghua Sun, Lihua Xie

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Zhengpeng ZengCenter of Health Management, Third Xiangya Hospital, Central South University, Changsha 410013. 974115114@qq.com.
Jinwen CaiDepartment of Respiratory and Critical Care Medicine, Third Xiangya Hospital, Central South University, Changsha 410013, China.
Yumei LiaoDepartment of Respiratory and Critical Care Medicine, Third Xiangya Hospital, Central South University, Changsha 410013, China.
Shenghua SunDepartment of Respiratory and Critical Care Medicine, Third Xiangya Hospital, Central South University, Changsha 410013, China. sunsh311@hotmail.com.
Lihua XieDepartment of Respiratory and Critical Care Medicine, Third Xiangya Hospital, Central South University, Changsha 410013, China. 13397219@qq.com.
Central South University · CN

Funding

the National Natural Science Foundation of China 82070048
6 · The paper itself

Abstract

Autophagy is a regulatory mechanism that packages damaged organelles, proteins, and pathogens to form vesicles and transports to lysosomes for degradation, enabling the recycle of useful components. Therefore, autophagy plays an important role in biological growth regulation and homeostasis. In the past two decades, growing evidence has shown that microRNA (miRNA) is closely related to autophagy. MiRNA-21 promotes or inhibits autophagy via regulating relevant pathways for different downstream target genes, and plays a role in tumors, ischemia-reperfusion injury, and other diseases.

Indexed as

MicroRNAsNeoplasmsReperfusion InjuryAutophagyHumansLysosomesMicroRNAsMIRN21 microRNA, humanautophagyischemia-reperfusion injurymicroRNA-21tumor

Identifiers

PMID36039591
PMCPMC10930284
OpenAlexW4293680664

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.