Evidence map›Paper›PMID 36045375›Full record

ReviewJournal of nanobiotechnology2022

Emerging trends in the nanomedicine applications of functionalized magnetic nanoparticles as novel therapies for acute and chronic diseases.

Sabyasachi Dash, Tuhin Das, Paritosh Patel, Pritam Kumar Panda, Mrutyunjay Suar, Suresh K Verma

Abstract readReview
In one paragraph

Review in Journal of nanobiotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Advances in Smart Responsive Nanofibers for Wound Healing.Biomimetics (Basel, Switzerland) · 2026
    Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Nucleic acid drugs: recent progress and future perspectives.Signal transduction and targeted therapy · 2024
    Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Assessment of CRISPRa-mediatedFrontiers in bioengineering and biotechnology · 2024
    Article
  15. Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sabyasachi Dash *Weill Cornell Medicine, Medical College of Cornell University, New York, NY, 10065, USA.
Tuhin Das *RayBiotech, Inc, 3607 Parkway Lane, Peachtree Corners, GA, 30092, USA.
Paritosh PatelSchool of Biotechnology, KIIT, Bhubaneswar, Odisha, 751024, India.
Pritam Kumar PandaDepartment of Physics and Astronomy, Uppsala University, 75120, Uppsala, Sweden. pritam.panda@physics.uu.se.
Mrutyunjay SuarSchool of Biotechnology, KIIT, Bhubaneswar, Odisha, 751024, India. msuar@kiitbiotech.ac.in.
Suresh K VermaSchool of Biotechnology, KIIT, Bhubaneswar, Odisha, 751024, India. sureshverma22@gmail.com.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
Department of Biotechnology, Ministry of Science and Technology, India BT/INF/22/SP42155/2021NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

High-quality point-of-care is critical for timely decision of disease diagnosis and healthcare management. In this regard, biosensors have revolutionized the field of rapid testing and screening, however, are confounded by several technical challenges including material cost, half-life, stability, site-specific targeting, analytes specificity, and detection sensitivity that affect the overall diagnostic potential and therapeutic profile. Despite their advances in point-of-care testing, very few classical biosensors have proven effective and commercially viable in situations of healthcare emergency including the recent COVID-19 pandemic. To overcome these challenges functionalized magnetic nanoparticles (MNPs) have emerged as key players in advancing the biomedical and healthcare sector with promising applications during the ongoing healthcare crises. This critical review focus on understanding recent developments in theranostic applications of functionalized magnetic nanoparticles (MNPs). Given the profound global economic and health burden, we discuss the therapeutic impact of functionalized MNPs in acute and chronic diseases like small RNA therapeutics, vascular diseases, neurological disorders, and cancer, as well as for COVID-19 testing. Lastly, we culminate with a futuristic perspective on the scope of this field and provide an insight into the emerging opportunities whose impact is anticipated to disrupt the healthcare industry.

Indexed as

COVID-19COVID-19 Drug TreatmentMagnetite NanoparticlesNanoparticlesChronic DiseaseCOVID-19 TestingHumansNanomedicinePandemicsMagnetite NanoparticlesMagnetic nanoparticlesNanomedicineNeurological disordersSi-RNA therapeuticsVascular diseases

Identifiers

PMID36045375
PMCPMC9428876

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.