Evidence map›Paper›PMID 36046118›Full record

ArticleExploration of targeted anti-tumor therapy2021

Alterations in the Ca

Alana L Cutliffe, Sharon L McKenna, Darshan S Chandrashekar, Alvin Ng, Ginny Devonshire, Rebecca C Fitzgerald, Tracey R O'Donovan, John J Mackrill

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Exploration of targeted anti-tumor therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. The L-type calcium channel CaV1.3: A potential target for cancer therapy.Journal of cellular and molecular medicine · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Alana L CutliffeDepartment of Physiology, University College Cork, BioSciences Institute, T12 YT20 Cork, Ireland.ORCID https://orcid.org/0000-0003-1383-0647
Sharon L McKennaCancer Research, UCC, Western Gateway Building, University College Cork, T12 XF62 Cork, Ireland.ORCID https://orcid.org/0000-0002-6764-6274
Darshan S ChandrashekarDepartment of Pathology, Molecular & Cellular, University of Alabama at Birmingham, Birmingham, AL 35233, USA.ORCID https://orcid.org/0000-0002-4295-9127
Alvin NgCancer Research UK Cambridge Institute, University of Cambridge Li Ka Shing Centre, Robinson Way, CB2 0RE Cambridge, UK.ORCID https://orcid.org/0000-0003-4672-0815
Ginny DevonshireCancer Research UK Cambridge Institute, University of Cambridge Li Ka Shing Centre, Robinson Way, CB2 0RE Cambridge, UK.ORCID https://orcid.org/0000-0002-1408-8176
Rebecca C FitzgeraldCancer Research UK Cambridge Institute, University of Cambridge Li Ka Shing Centre, Robinson Way, CB2 0RE Cambridge, UK.ORCID https://orcid.org/0000-0002-3434-3568
Tracey R O'DonovanCancer Research, UCC, Western Gateway Building, University College Cork, T12 XF62 Cork, Ireland.ORCID https://orcid.org/0000-0003-0282-6888
John J MackrillDepartment of Physiology, University College Cork, BioSciences Institute, T12 YT20 Cork, Ireland.ORCID https://orcid.org/0000-0003-2473-129X
University College Cork · IEUniversity of Cambridge · GBUniversity of Alabama at Birmingham · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: To investigate alterations in transcription of genes, encoding Ca Methods: The expression of 275 transcripts, encoding components of the Ca Results: Of the 275 Ca Conclusions: This study has unveiled alterations of the Ca

Indexed as

acid-sensingacid-sensing ion channel 4Ca2+ toolkitjunctophilin 1Oesophageal adenocarcinomasecretory pathway Ca2+ ATPase 2transient receptor potential ion channel melastatin 5voltage-gated Ca2+ channel subunits

Identifiers

PMID36046118
PMCPMC9400700
OpenAlexW4200366699

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.