Evidence map›Paper›PMID 36046715›Full record

ArticleAnnals of medicine and surgery (2012)2022

Increasing challenges of malaria control in sub-Saharan Africa: Priorities for public health research and policymakers.

Habeebullah Jayeola Oladipo, Yusuf Amuda Tajudeen, Iyiola Olatunji Oladunjoye, Sodiq Inaolaji Yusuff, Rashidat Onyinoyi Yusuf, Egbewande Muyiwa Oluwaseyi, Muili Opeyemi AbdulBasit, Yusuff Adebayo Adebisi, Mona Said El-Sherbini

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of medicine and surgery (2012), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 112 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
112citing papers in PubMed, 12 pooled it
30.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

112 citing papers in PubMed, 12 syntheses or guidelines pooled it, 158 citations in OpenAlex.

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  10. Mapping Antimalarial Drug Resistance in Mozambique: A Systematic Review ofInternational journal of molecular sciences · 2024
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  17. Selective targeting ofAntimicrobial agents and chemotherapy · 2026
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52 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Habeebullah Jayeola OladipoFaculty of Pharmaceutical Sciences, University of Ilorin, P.M.B. 1515, Ilorin, 240003, Nigeria.
Yusuf Amuda TajudeenDepartment of Microbiology, Faculty of Life Sciences, University of Ilorin, P.M.B. 1515, Ilorin, 240003, Nigeria.
Iyiola Olatunji OladunjoyeDepartment of Microbiology, Faculty of Life Sciences, University of Ilorin, P.M.B. 1515, Ilorin, 240003, Nigeria.
Sodiq Inaolaji YusuffDepartment of Medicine, Faculty of Clinical Sciences, Obafemi Awolowo University, Ibadan-Ife Rd, 220101, Ife, Osun State, Nigeria.
Rashidat Onyinoyi YusufFaculty of Pharmaceutical Sciences, University of Ilorin, P.M.B. 1515, Ilorin, 240003, Nigeria.
Egbewande Muyiwa OluwaseyiFaculty of Pharmaceutical Sciences, University of Ilorin, P.M.B. 1515, Ilorin, 240003, Nigeria.
Muili Opeyemi AbdulBasitFaculty of Basic Medical Sciences, Ladoke Akintola University of Technology, P.M.B 4000, Ogbomosho, Oyo State, Nigeria.
Yusuff Adebayo AdebisiFaculty of Pharmacy, University of Ibadan, Ibadan, Nigeria.
Mona Said El-SherbiniDepartment of Medical Parasitology, Faculty of Medicine, Cairo University, Cairo, 11562, Egypt.
University of Ilorin · NGCairo University · EGLadoke Akintola University of Technology · NGObafemi Awolowo University · NGUniversity of Ibadan · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ever-increasing cases and mortality due to malaria remains one of the most important public health threats, especially in sub-Saharan Africa-where this burden is considerably high. In 2020, sub-Saharan Africa accounted for about 95% of all cases and 96% of all malaria deaths with about 80% of these deaths reported in children under the age of 5. This review, adopting a public health focus, aimed to understand the challenges of malaria control in sub-Saharan Africa despite ongoing public health interventions. Our review highlights two important findings. First, the increasing resistance of malaria parasites to artemisinin-based combination therapy (ACT) and its partner drugs coupled with increased vector resistance to pyrethroids and insecticides is reversing the progress of public health interventions in keeping malaria under control. Second, the wanning for the efficacy of the WHO-approved vaccine i.e. RTS,S from 60 to 70% following 18 months of observation, and its short-term availability remains an impediment to achieving the WHO target of producing malaria vaccines with more than 75% efficacy by 2030. Our findings underline the need to reassess research priorities with a focus on vaccine production in sub-Saharan Africa. Furthermore, African governments and policymakers must be committed to invest both the political and financial capital in vaccine production and distribution.

Indexed as

Malaria controlMalaria vaccinePolicymakersSub-Saharan AfricaWHO

Identifiers

PMID36046715
PMCPMC9421173
OpenAlexW4292819221

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.