Evidence map›Paper›PMID 36046828›Full record

ArticleFrontiers in pharmacology2022

A synthetic BBB-permeable tripeptide GCF confers neuroprotection by increasing glycine in the ischemic brain.

Juan Chen, Yang Zhuang, Ya Zhang, Huabao Liao, Rui Liu, Jing Cheng, Zhifeng Zhang, Jiangdong Sun, Jingchen Gao, Xiyuran Wang and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Ile-Pro-Pro attenuates sympathetic activity and hypertension.Journal of physiology and biochemistry · 2024
    Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Juan ChenDepartment of Neurology, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Yang ZhuangDepartment of Physiology, School of Medicine, Wuhan University, Wuhan, China.
Ya ZhangDepartment of Physiology, School of Medicine, Wuhan University, Wuhan, China.
Huabao LiaoDepartment of Physiology, School of Medicine, Wuhan University, Wuhan, China.
Rui LiuDepartment of Physiology, School of Medicine, Wuhan University, Wuhan, China.
Jing ChengDepartment of Physiology, School of Medicine, Wuhan University, Wuhan, China.
Zhifeng ZhangDepartment of Physiology, School of Medicine, Wuhan University, Wuhan, China.
Jiangdong SunDepartment of Pathophysiology, School of Basic Medicine, Institute of Neuroregeneration and Neurorehabilitation, Qingdao University, Qingdao, China.
Jingchen GaoDepartment of Pathophysiology, School of Basic Medicine, Institute of Neuroregeneration and Neurorehabilitation, Qingdao University, Qingdao, China.
Xiyuran WangDepartment of Pathophysiology, School of Basic Medicine, Institute of Neuroregeneration and Neurorehabilitation, Qingdao University, Qingdao, China.
Shujun ChenDepartment of Pathophysiology, School of Basic Medicine, Institute of Neuroregeneration and Neurorehabilitation, Qingdao University, Qingdao, China.
Liang ZhangKrembil Research Institute, University Health Network, University of Toronto, Toronto, ON, Canada.
Fengyuan CheCentral Laboratory, Department of Neurology, Linyi People's Hospital, Qingdao University, Linyi, China.
Qi WanDepartment of Pathophysiology, School of Basic Medicine, Institute of Neuroregeneration and Neurorehabilitation, Qingdao University, Qingdao, China.
Wuhan University · CNQingdao University · CNHuazhong University of Science and Technology · CNKrembil Research InstituteLinyi People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BBBglycineischemic strokeneuroprotectiontripeptide

Identifiers

PMID36046828
PMCPMC9420865
OpenAlexW4291383118

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.