Evidence map›Paper›PMID 36047706›Full record

ArticleEpigenetics2022

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Lucas Alvizi, Luciano Abreu Brito, Gerson Shigeru Kobayashi, Bárbara Bischain, Camila Bassi Fernandes da Silva, Sofia Ligia Guimaraes Ramos, Jaqueline Wang, Maria Rita Passos-Bueno

Open access · hybridAbstract read
In one paragraph

Article in Epigenetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Genetic-epigenetic interactions (meQTLs) in orofacial clefts etiology.medRxiv : the preprint server for health sciences · 2025
    Article
  5. MicroRNAs and Gene Regulatory Networks Related to Cleft Lip and Palate.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Lucas AlviziCentro de Pesquisas sobre o Genoma Humano e Células Tronco, Universidade de São Paulo, Brasil.
Luciano Abreu BritoCentro de Pesquisas sobre o Genoma Humano e Células Tronco, Universidade de São Paulo, Brasil.
Gerson Shigeru KobayashiCentro de Pesquisas sobre o Genoma Humano e Células Tronco, Universidade de São Paulo, Brasil.
Bárbara BischainCentro de Pesquisas sobre o Genoma Humano e Células Tronco, Universidade de São Paulo, Brasil.
Camila Bassi Fernandes da SilvaCentro de Pesquisas sobre o Genoma Humano e Células Tronco, Universidade de São Paulo, Brasil.
Sofia Ligia Guimaraes RamosCentro de Pesquisas sobre o Genoma Humano e Células Tronco, Universidade de São Paulo, Brasil.
Jaqueline WangCentro de Pesquisas sobre o Genoma Humano e Células Tronco, Universidade de São Paulo, Brasil.
Maria Rita Passos-BuenoCentro de Pesquisas sobre o Genoma Humano e Células Tronco, Universidade de São Paulo, Brasil.
Universidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-syndromic cleft lip with or without cleft palate (NSCLP), the most common human craniofacial malformation, is a complex disorder given its genetic heterogeneity and multifactorial component revealed by genetic, epidemiological, and epigenetic findings. Epigenetic variations associated with NSCLP have been identified; however, functional investigation has been limited. Here, we combined a reanalysis of NSCLP methylome data with genetic analysis and used both

Indexed as

Cleft LipCleft PalateMicroRNAsAnimalsDNA MethylationGenetic Predisposition to DiseaseHumansHypoxiaPolymorphism, Single NucleotideZebrafishMicroRNAsMIRN152 microRNA, humancleft lip/palatecraniofacial marformationEpigeneticsmicroRNA

Identifiers

PMID36047706
PMCPMC9665146
OpenAlexW4294025272

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.