Evidence map›Paper›PMID 36047808›Full record

ReviewAntioxidants & redox signaling2023

KRIT1: A Traffic Warden at the Busy Crossroads Between Redox Signaling and the Pathogenesis of Cerebral Cavernous Malformation Disease.

Andrea Perrelli, Chiara Ferraris, Elisa Berni, Angela J Glading, Saverio Francesco Retta

Open access · greenAbstract readReview
In one paragraph

Review in Antioxidants & redox signaling, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Possible correlation between KRIT1 variant and non-atherosclerotic vasculopathy resulting in ischemic stroke.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Article
  5. Review
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  7. Article
  8. Article
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  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Andrea PerrelliDepartment of Clinical and Biological Sciences, University of Torino, Torino, Italy.
Chiara FerrarisDepartment of Clinical and Biological Sciences, University of Torino, Torino, Italy.
Elisa BerniDepartment of Clinical and Biological Sciences, University of Torino, Torino, Italy.
Angela J GladingDepartment of Pharmacology and Physiology, University of Rochester Medical Center, Rochester, New York, USA.
Saverio Francesco RettaDepartment of Clinical and Biological Sciences, University of Torino, Torino, Italy.ORCID 0000-0001-9761-2959
Torino e-district · ITUniversity of Rochester Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Hemangioma, Cavernous, Central Nervous SystemEndothelial CellsHumansInflammationKRIT1 ProteinMicrotubule-Associated ProteinsOxidation-ReductionSignal TransductionKRIT1 ProteinKRIT1 protein, humanMicrotubule-Associated Proteinscerebral cavernous malformation (CCM)cerebrovascular diseaseendothelial cell adhesion and barrier functionendothelial-to-mesenchymal transition (EndMT)GTPasesinflammationKRIT1MAPKsNADPH oxidasesoxidative post-translational modifications (Ox-PTMs)oxidative stressreactive oxygen species (ROS)redox homeostasis and signaling

Identifiers

PMID36047808
PMCPMC10039281
OpenAlexW4294018106

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.